Effect of Aromatics on Lung Mucociliary Clearance in Patients with Chronic Airways Obstruction

Hasani, A.; Pavia, D; Toms, N.; Dilworth, Paul; Agnew, J. E.

doi:10.1089/10755530360623356

Cited by 36 publications

(15 citation statements)

References 29 publications

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“…A lavender fragranced cleansing gel had a significant transient effect of improving mood and making people feel more relaxed (Field et al, 2005). Aromatic materials, topically applied, showed positive effects on lung mucus clearance in patients with chronic airway obstruction (Hasani et al, 2003). Even foot soaking in warm water containing lavender essential oil followed by reflexology treatment with jojoba oil containing lavender, appeared to be effective for alleviating fatigue in terminally ill cancer patients (Kohara et al, 2004).…”

Section: Massagementioning

confidence: 99%

Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review

Edris

2007

Phytotherapy Research

1,095

688

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Essential oils and their volatile constituents are used widely to prevent and treat human disease. The possible role and mode of action of these natural products is discussed with regard to the prevention and treatment of cancer, cardiovascular diseases including atherosclerosis and thrombosis, as well as their bioactivity as antibacterial, antiviral, antioxidants and antidiabetic agents. Their application as natural skin penetration enhancers for transdermal drug delivery and the therapeutic properties of essential oils in aroma and massage therapy will also be outlined.

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Section: Massagementioning

confidence: 99%

Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review

Edris

2007

Phytotherapy Research

1,095

688

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“…14 The literature search for the current study used PubMed and CISCOM databases and identified eight randomized controlled trials using aroma alone compared to placebo. [15][16][17][18][19][20][21][22] These studies varied greatly in subject numbers (4-313) and had poorly described methods. None evaluated the blinding of the placebo/control intervention (or equipoise) in relation to odor.…”

Section: Introduction Imentioning

confidence: 99%

A Single-Blinded, Randomized Pilot Study Evaluating the Aroma of Lavandula augustifolia as a Treatment for Mild Insomnia

Lewith

Godfrey

Prescott

2005

The Journal of Alternative and Complementary Medicine

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Background: Insomnia is the most common of all sleep complaints and is under-researched. The current treatments of choice are conventional hypnotics agents, but these have potential for serious adverse reactions. Uncontrolled and anecdotal evidence suggests that lavender oil is an effective treatment for insomnia, but this has not been formally investigated.Objectives: The aims of this study were to evaluate the proposed trial methodology and the efficacy of Lavandula augustifolia (lavender) on insomnia.Interventions: Interventions consisted of Lavandula augustifolia (treatment) and sweet almond oil as placebo/control. The aroma was supplied via an Aromastream device (Tisserand Aromatherapy, Sussex, UK).Design: This was a pilot study with randomized, single-blind, cross-over design (baseline, two treatment periods, and a washout period, each of 1 week duration).Subjects and setting: Volunteers with defined insomnia treated on a domiciliary basis participated in the study.Outcome measures: Outcomes were assessed with the following: Pittsburgh Sleep Quality Index (PSQI) indicating insomnia (score Ͼ5 at entry); Borkovec and Nau (B&N) Questionnaire evaluating treatment credibility; and Holistic Complementary and Alternative Medicine Questionnaire (HCAMQ) assessing attitudes to CAM and health beliefs.Results: Ten (10) volunteers (5 male and 5 female) were entered and completed the 4 week study. Lavender created an improvement of Ϫ2.5 points in PSQI (p ϭ 0.07, 95% CI Ϫ4.95 to Ϫ0.4). Each intervention was equally credible and belief in CAM did not predict outcome. Women and younger volunteers with a milder insomnia improved more than others. No period or carry-over effect was observed. Conclusion:The methodology for this pilot study appeared to be appropriate. Outcomes favor lavender, and a larger trial is required to draw definitive conclusions.

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“…21 Compounds that contain menthol and/or camphor have also been shown to reduce respiratory rate and restlessness in children with acute bronchitis, 22,23 reduce evoked cough in healthy adults, 24 and improve mucociliary clearance in adults with chronic bronchitis. 25 The improved ability of children to sleep with VR is noteworthy. A child's inability to sleep during a URI can be disruptive to their daytime functioning as well as the functioning of other family members.…”

Section: Discussionmentioning

confidence: 99%

Vapor Rub, Petrolatum, and No Treatment for Children With Nocturnal Cough and Cold Symptoms

2010

PEDIATRICS

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OBJECTIVE-To determine if a single application of a vapor rub (VR) or petrolatum is superior to no treatment for nocturnal cough, congestion, and sleep difficulty caused by upper respiratory tract infection.METHODS-Surveys were administered to parents on 2 consecutive days-on the day of presentation when no medication had been given the previous evening, and the next day when VR ointment, petrolatum ointment, or no treatment had been applied to their child's chest and neck before bedtime according to a partially double-blinded randomization scheme.RESULTS-There were 138 children aged 2 to 11 years who completed the trial. Within each study group, symptoms were improved on the second night. Between treatment groups, significant differences in improvement were detected for outcomes related to cough, congestion, and sleep difficulty; VR consistently scored the best, and no treatment scored the worst. Pairwise comparisons demonstrated the superiority of VR over no treatment for all outcomes except rhinorrhea and over petrolatum for cough severity, child and parent sleep difficulty, and combined symptom score. Petrolatum was not significantly better than no treatment for any outcome. Irritant adverse effects were more common among VR-treated participants.CONCLUSIONS-In a comparison of VR, petrolatum, and no treatment, parents rated VR most favorably for symptomatic relief of their child's nocturnal cough, congestion, and sleep difficulty caused by upper respiratory tract infection. Despite mild irritant adverse effects, VR provided symptomatic relief for children and allowed them and their parents to have a more restful night than those in the other study groups. Commenting on camphor-containing products, in 1994 the American Academy of Pediatrics Committee on Drugs wrote, "Since alternative agents exist for all indications for camphor therapy, other therapeutic agents that do not contain camphor should be considered." 13 The "alternative agent" for cough and cold symptoms cited by the Committee in 1994, dextromethorphan, was subsequently not recommended by that committee 3 years later in a policy statement on dextromethorphan use. 4 Dextromethorphan continues not to be recommended, 14 and therefore the question of whether clinicians can recommend topical preparations containing camphor, menthol, and eucalyptus oil for URI symptoms in children requires reevaluation. KeywordsWith no contemporary evidence that supports or refutes the efficacy in children with URIs, this study sought to determine if a single application of a vapor rub (VR) or petrolatum is superior to no treatment for nocturnal cough, congestion, and sleep difficulty caused by URIs. We hypothesized that VR or petrolatum would be superior to no treatment for relief of nocturnal symptoms and that VR would be superior to petrolatum. METHODSFrom October 2008 through February 2010, patients were recruited from a universityaffiliated pediatric practice in Hershey, Pennsylvania. Eligible patients were aged 2 to 11 years with symptoms attributed to URIs...

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Effect of Aromatics on Lung Mucociliary Clearance in Patients with Chronic Airways Obstruction

Abstract: Our data, thus, provide objective evidence of a positive effect of aromatics inunction on mucus clearance in chronic airways obstruction.

Cited by 36 publications

References 29 publications

Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review

Pharmaceutical and therapeutic Potentials of essential oils and their individual volatile constituents: a review

A Single-Blinded, Randomized Pilot Study Evaluating the Aroma of Lavandula augustifolia as a Treatment for Mild Insomnia

Vapor Rub, Petrolatum, and No Treatment for Children With Nocturnal Cough and Cold Symptoms

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