“…Hormone deficiency in brain regions responsible for cognitive activities leads to perceptual changes (12) , which can interfere with information processing and impair language development. Delays in the beginning of oral language production, comprehension difficulties, reduced vocabulary and morphosyntactic changes have been reported in children with CH (1,8,13,21,22) , as well as changes in behavior such as hyperactivity, impulsivity, sleep disorders, agitation, among others (1,10,14,19,23,24) , which may contribute to deficits in school learning and social integration of children. Motor impairment has also been reported with regards to delayed inhibition of primitive reflexes, alterations in static and dynamic balance and, especially, gross and fine motor coordination (14,15,17,18,25) .…”