Effect of B<sub>1</sub>Inhomogeneity on Breast MR Imaging at 3.0 T

Kuhl, Christiane K.; Kooijman, Hendrik; Gieseke, J; Schild, H.

doi:10.1148/radiol.2443070266

Cited by 104 publications

(95 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, it may also represent a limitation as inhomogeneities of the radiofrequency excitation field could reduce the accuracy of [Gd] measurement (22). At present, the extent of these radiofrequency excitation field inhomogeneities is not clear, although the tumors, most of which are quite centrally located, are likely to avoid the extremes of the variations.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Dynamic contrast-enhanced MRI in ovarian cancer: Initial experience at 3 tesla in primary and metastatic disease

et al. 2010

View full text Add to dashboard Cite

The aim of this study was to develop and demonstrate a methodology for dynamic contrast-enhanced MRI at 3 T in patients with advanced ovarian cancer and to report the results from pharmacokinetic modeling of the data. Nineteen patients with suspected advanced ovarian carcinoma (FIGO stage 3 or higher) were enrolled in this prospective study. Up to three marker lesions were identified: primary ovarian mass, omental ''cake'', and peritoneal deposits. Dynamic contrastenhanced MRI was performed using a three-dimensional T 1 -weighted gradient-echo acquisition with a temporal resolution of 1.6 sec, following intravenous administration of 0.1 mmol/ kg gadobutrol. Precontrast T 1 mapping, using an inversion-recovery fast gradient-echo sequence, was also performed. Imaging was completed in 18/19 patients, although two were subsequently excluded based on pathology results. Pharmacokinetic modeling of the data was performed according to the extended Kety model, using an arterial input function formed by concatenation of the Fritz-Hansen and Weinmann curves. No statistically significant differences were found between the results for the three marker lesions. In the future, this work will allow kinetic modeling results from ovarian dynamic contrast-enhanced MRI to be correlated with response to treatment. The high temporal resolution allows good characterization of the rapid contrast agent uptake in these vascular tumors.

show abstract

Section: Discussionmentioning

confidence: 99%

“…This has been shown to improve image quality and diagnostic confidence in the breast (21), although the inhomogeneous radiofrequency field near the edge of the body raises concerns over consistency of lesion enhancement and consequently over the robustness of lesion detection (22).…”

mentioning

confidence: 99%

Dynamic contrast-enhanced MRI in ovarian cancer: Initial experience at 3 tesla in primary and metastatic disease

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Generally, a 3.0-T scanner offers a high SNR and high spectral resolution. However, it is debatable whether a 3.0-T scanner is adaptable for breast examinations because of inhomogeneity of B0 and B1 and the strong susceptibility effect (30,31). In our hospital a 3.0-T scanner has been used for breast examinations to obtain high spatial resolution of dynamic contrast-enhanced imaging and high spectral resolution at MRS.…”

Section: Discussionmentioning

confidence: 99%

¹H‐magnetic resonance spectroscopy of the breast at 3.0‐T: Comparison of results obtained before and after administration of gadolinium‐based contrast agent

Kawai

Naganawa

Satake

et al. 2011

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Purpose: To assess the effects of gadolinium-based contrast agent (GBCA) on 1 H-magnetic resonance spectroscopy (MRS) of the breast at 3.0-T. Materials and Methods:Patients (n ¼ 98) with breast cancer (98 lesions) underwent MRS (point-resolved spectroscopy sequence [PRESS]; TR/TE, 2000/100 msec; voxel size, 15 Â 15 Â 15 mm) before the administration of GBCA. In 52 of those patients, MRS was also performed after the administration of GBCA. The voxel-of-interest (VOI) was placed by referring to the noncontrastenhanced MRI (diffusion-weighted images combined with fat-suppressed T2-weighted images). We reviewed and graded the appropriateness of VOI location compared to the correlating enhancement lesions. Integral values of the choline peak at a frequency of 3.2 ppm on MRS were compared before and after the administration of GBCA. Results:The VOI was placed correctly in 64 lesions (65%), although the VOI was placed outside the targeted lesion in 34 lesions (35%). The integral value of the choline peak on MRS decreased significantly after the administration of GBCA (P < 0.001).Conclusion: Accumulation of GBCA in breast cancer could affect the choline peak on MRS. MRS of breast cancer at 3.0-T can be recommended to be acquired before contrast-enhanced study; however, some problems remain in VOI placement with reference to the noncontrast-enhanced study.

show abstract

“…[17][18][19] Nevertheless, due to the wide availability of 3T MRI scanners, many clinical breast MRI studies are also done at 3T. The purpose of this preliminary work is to compare the measurement consistency in breast volume (BV), fibroglandular tissue volume (FV), and percent density (PD) using four different scanners, two at 1.5T and two at 3T.…”

Section: Introductionmentioning

confidence: 99%

Consistency of breast density measured from the same women in four different MR scanners

et al. 2012

View full text Add to dashboard Cite

Purpose:To compare the breast volume (BV), fibroglandular tissue volume (FV), and percent density (PD) measured from breast MRI of the same women using four different MR scanners. Methods:The study was performed in 34 healthy Asian volunteers using two 1.5T (GE and Siemens) and two 3T (GE and Philips) MR scanners. The BV, FV, and PD were measured on nonfat-suppressed T1-weighted images using a comprehensive computer algorithm-based segmentation method. The scanner-to-scanner measurement difference, and the coefficient of variation (CV) among the four scanners were calculated. The measurement variation between two density morphological patterns presenting as the central type and the intermingled type was separately analyzed and compared. Results: All four scanners provided satisfactory image quality allowing for successful completion of the segmentation processes. The measured parameters between each pair of MR scanners were highly correlated, with R 2 ≥ 0.95 for BV, R 2 ≥ 0.99 for FV, and R 2 ≥ 0.97 for PD in all comparisons. The mean percent differences between each pair of scanners were 5.9%-7.8% for BV, 5.3%-6.5% for FV, 4.3%-7.3% for PD; with the overall CV of 5.8% for BV, 4.8% for FV, and 4.9% for PD. The variation of FV was smaller in the central type than in the intermingled type (p = 0.04). Conclusions:The results showed that the variation of FV and PD measured from four different MR scanners is around 5%, suggesting the parameters measured using different scanners can be used for a combined analysis in a multicenter study.

show abstract

Effect of B₁Inhomogeneity on Breast MR Imaging at 3.0 T

Cited by 104 publications

References 1 publication

Dynamic contrast-enhanced MRI in ovarian cancer: Initial experience at 3 tesla in primary and metastatic disease

Dynamic contrast-enhanced MRI in ovarian cancer: Initial experience at 3 tesla in primary and metastatic disease

¹H‐magnetic resonance spectroscopy of the breast at 3.0‐T: Comparison of results obtained before and after administration of gadolinium‐based contrast agent

Consistency of breast density measured from the same women in four different MR scanners

Contact Info

Product

Resources

About

Effect of B1Inhomogeneity on Breast MR Imaging at 3.0 T

Cited by 104 publications

References 1 publication

Dynamic contrast-enhanced MRI in ovarian cancer: Initial experience at 3 tesla in primary and metastatic disease

Dynamic contrast-enhanced MRI in ovarian cancer: Initial experience at 3 tesla in primary and metastatic disease

1H‐magnetic resonance spectroscopy of the breast at 3.0‐T: Comparison of results obtained before and after administration of gadolinium‐based contrast agent

Consistency of breast density measured from the same women in four different MR scanners

Contact Info

Product

Resources

About

Effect of B₁Inhomogeneity on Breast MR Imaging at 3.0 T

¹H‐magnetic resonance spectroscopy of the breast at 3.0‐T: Comparison of results obtained before and after administration of gadolinium‐based contrast agent