Effect of Bay Leaf (Syzygium polyanthum) Extract on Antioxidant Activity, MDA Levels, and Liver Histopathology Feature of Ethambutol Induced Wistar Rats

Suwito, Bambang Edi; Shanty, Lea Maera; Gumilang, Retna; Handayani, Handayani; Ulhaq, Renata Alya

doi:10.33086/ijmlst.v4i2.2471

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…Tannins also consist of polyphenolic compounds which have antibacterial, antioxidant and astringent activities. 31,32,33 In plants, tannins can be found in various organs, such as leaves, stems, roots, fruit and bark. Tannin is stored in cell vacuoles in tissue.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis of Curry Leaf Extract (Murraya koenigii L.) as a Potential Animal Feed and Medicinal Ingredient

Al Arif,

Warsito,

Lamid

et al. 2024

Pharmacogn J.

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Herbal plants have been used for centuries as traditional medicine to treat various diseases. Green plants generally contain phytochemical compounds, such as vegetables and plants that add aroma to dishes, one of which is curry leaves (Murraya Koenigii). This research aims to identify the phytochemical compounds contained in curry leaves. This research was carried out from August 2023 to October 2023. The curry leaves that were obtained were converted into extract form and then the extract was tested for the content of alkaloids, flavonoids, saponins, phenolics and tannins. The research results showed that curry leaf extract contained 23.73% alkaloids, 1.24% flavonoids, 8.74% saponins, 4.4% phenolics, and 5.2% tannins. Alkaloids in plants have a role as a defense against biotic and abiotic disorders. The benefits of flavonoids in plants include anti-mutagenic, anti-inflammatory, antioxidant and anti-carcinogenic. Saponins have various benefits in the health sector, including being able to reduce cholesterol concentrations in the blood. Polyphenols have good antioxidant power because this group can provide electrons to neutralize free radical electrons formed in the body. Tannins also consist of polyphenolic compounds which have antibacterial, antioxidant and astringent activities. The results of the analysis regarding the content of secondary metabolite compounds in curry leaf extract play an important role in the development of future medicines and need to be carried out to provide knowledge to the public. This study can be a basis for bioactive content for further research to expand the use of medicinal plants in the future, especially curry plants.

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Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis of Curry Leaf Extract (Murraya koenigii L.) as a Potential Animal Feed and Medicinal Ingredient

Al Arif,

Warsito,

Lamid

et al. 2024

Pharmacogn J.

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“…Its leaves emit a pleasant aroma when crushed [ 94 ]. S. polyanthum is widely used as a traditional remedy for a range of infections, such as diabetes [ 95 ], cardiovascular disease [ 96 ], hyperlipidemia [ 97 ], anemia [ 98 ], kidney disease [ 99 ], liver disease [ 100 ], gout [ 101 ], oxidative disease [ 102 ], and some bacterial diseases [ 103 ].…”

Section: Syzygnium Polyanthummentioning

confidence: 99%

Potential of Syzygnium polyanthum as Natural Food Preservative: A Review

Julizan

Ishmayana

Zainuddin

et al. 2023

Foods

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Food preservation is one of the strategies taken to maintain the level of public health. Oxidation activity and microbial contamination are the primary causes of food spoilage. For health reasons, people prefer natural preservatives over synthetic ones. Syzygnium polyanthum is widely spread throughout Asia and is utilized as a spice by the community. S. polyanthum has been found to be rich in phenols, hydroquinones, tannins, and flavonoids, which are potential antioxidants and antimicrobial agents. Consequently, S. polyanthum presents a tremendous opportunity as a natural preservative. This paper reviews recent articles about S. polyanthum dating back to the year 2000. This review summarizes the findings of natural compounds presented in S. polyanthum and their functional properties as antioxidants, antimicrobial agents, and natural preservatives in various types of food.

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Histopathological of Mice (Mus musculus) Liver Induced by Lead (Pb) Orally

Kodariah,

Efrida,

Aditya

et al. 2023

IJMLST

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Lead (Pb) is a prominent heavy metal emitted by motor vehicle exhausts, factory and mining fumes. Its presence in the atmoshpere can endure for up to seven days, posing a considerable risk of contaminating surrounding food and beverages. Lead enters the body through inhalation and the skin. Lead can also enter the human body via the oral route and accumulate in the body. It causes health problems such as oxidative stress and damage human organs such as the kidneys and liver. This research aims to examine the effect of oral lead exposure on the liver histopathology of Swiss Webster strain mice (Mus musculus). Employing a non-probability sampling technique, 25 male mice were divided into 5 groups: negative control, K2, K3, K4 and K5. These mice were administered a daily oral dose of 0.5 mL and subsequently euthanized in CO2 chamber the following week for liver dissection. The findings reveal signs of hydropic degeneration characterized by cellular swelling, irregular shapes, and disrupted organelles in groups K2, K3, K4, and K5. In addition, the mean degree of liver damage was observed as 0 for the negative control, 1 for group K2, 1 for group K3, 2 for group K4, and 3 for group K5. In conclsuin, this study confirms that lead exposure can result in dentrimenal liver histopathology changes in mice.

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Effect of Bay Leaf (Syzygium polyanthum) Extract on Antioxidant Activity, MDA Levels, and Liver Histopathology Feature of Ethambutol Induced Wistar Rats

Cited by 3 publications

References 19 publications

Phytochemical Analysis of Curry Leaf Extract (Murraya koenigii L.) as a Potential Animal Feed and Medicinal Ingredient

Phytochemical Analysis of Curry Leaf Extract (Murraya koenigii L.) as a Potential Animal Feed and Medicinal Ingredient

Potential of Syzygnium polyanthum as Natural Food Preservative: A Review

Histopathological of Mice (Mus musculus) Liver Induced by Lead (Pb) Orally

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