Effect of beta-alanine supplementation on the onset of blood lactate accumulation (OBLA) during treadmill running: Pre/post 2 treatment experimental design

Jordan, Thomas; Lukaszuk, Judith M.; Misic, Mark M.; Umoren, Josephine

doi:10.1186/1550-2783-7-20

Cited by 59 publications

(87 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…While some results have shown an increase in TTE (Stout et al, 2006Hill et al, 2007;, others have reported no significant change Jordan et al, 2010). Similar to previous literature, the present study found no significant treatment effect on VO 2peak .…”

Section: P-valuesupporting

confidence: 89%

The effects of beta‐alanine supplementation on physical working capacity at heart rate threshold

Smith‐Ryan

Woessner

Melvin

et al. 2013

Clin Physio Funct Imaging

View full text Add to dashboard Cite

Beta-alanine (BA) supplementation has been shown to delay neuromuscular fatigue as a result of increased muscle carnosine concentrations. Carnosine has also been found in brain and cardiac tissue. The physical working capacity test at heart rate threshold (PWC(HRT)) is a global estimate of the onset of fatigue during exercise, influenced by central and peripheral factors. The purpose of this study was to determine the effects of 28 days of BA supplementation on the PWC(HRT). Thirty subjects (mean ± SD; age: 21·0 ± 2·1 years; body mass: 72·7 ± 14·5 kg; height: 170·1 ± 7·9 cm) were randomly assigned to BA (n = 15) or placebo (PL, n = 15) groups. Testing included eight to nine total visits: an enrolment day, physical screening, peak oxygen consumption (V(·)O(2peak)) and two PWC(HRT) assessments over 4 days. Significant differences existed between BA and PL for PWC(HRT) (P = 0·001; mean∆: BA∆ = +24·2 watts, PL∆ = +11·2 watts), but not for V(·)O(2peak) (P = 0·222), time to exhaustion (TTE; P = 0·562) or ventilatory threshold (VT; P = 0·134). Results suggest that BA may increase heart rate training threshold. These results, in combination with one previous study reporting a potential effect of BA on HR, suggest that future studies should evaluate both central and peripheral aspects of fatigue with BA intake.

show abstract

Section: P-valuesupporting

confidence: 89%

The effects of beta‐alanine supplementation on physical working capacity at heart rate threshold

Smith‐Ryan

Woessner

Melvin

et al. 2013

Clin Physio Funct Imaging

View full text Add to dashboard Cite

show abstract

“…Jordan et al [14,19] found that BA supplementation significantly delayed the onset of blood lactate during incremental exercise testing. Despite using the same supplementation time period as the present trial (28-days) the authors did not report changes in time to exhaustion, total exercise time or other measures consistent with the results of the present trial, which prevents the ability to directly compare findings of [14] with our results. Del Favero et al [19] reported a significant increase in time to exhaustion during treadmill exercise testing in healthy individuals aged 60-80 years.…”

Section: Discussionmentioning

confidence: 99%

“…After noting the results of a previous randomized controlled trial with a similar research design [14], the following data was entered into G*Power3; effect size (ES)=0.5, alpha level (α)=0.05, power (1-β)=0.8, r=0.5, 2 groups and 0 correlation between groups. A priori estimation indicated that 12 participants, with six in each treatment group, would be the minimum number for detection of the intervention effect using ANOVA with repeated measures for within and between group interactions.…”

Section: Participantsmentioning

confidence: 99%

The Effect of 28 Days of Beta-alanine Supplementation on Exercise Capacity and Insulin Sensitivity in Individuals with Type 2 Diabetes Mellitus: A Randomised, Double-blind and Placebo-controlled Pilot Trial

RS¹,

WR²

2016

Sports Nutr Ther

View full text Add to dashboard Cite

Objective: To determine the effects of 28 days of BA supplementation on exercise capacity as measured by time to volitional failure during an incremental treadmill test in individuals with T2DM.Methods: Participants undertook a modified Naughton treadmill test to assess exercise capacity and a fasting blood test before and after the supplementation period. Participants consumed four grams of BA (n=7) per day or the equivalent amount of maltodextrin (n=5) for 28 days and maintained their lifestyle habits during the supplementation period.Results: Twenty-eight days of BA supplementation significantly increased the time to volitional failure during the treadmill exercise test by m=135.2, SD=(± 81.3) seconds (21%), p=0.001, as detected by general linear model analysis with repeated measures. There was significant interaction of pre to post by group in fasting blood glucose, p=0.046. A strong negative correlation was found between the changes in the time to volitional failure during exercise testing and the changes in fasting blood glucose in the beta-alanine treatment group, r=− 0.92, p<0.01. Conclusion:This study has provided new evidence that BA supplementation can increase exercise capacity in individuals with T2DM.

show abstract

“…Hasta el momento, las conclusiones tras el uso de la β-alanina son muy variadas debido a que los estudios han sido muy dispares, utilizando test muy diferentes (48)(49)(50)(51)(52)(53)(54)(55)(56)(57). En general, en ejercicios repetidos de alta intensidad se observa una mejora del trabajo total y de la potencia media (53) o de la marca conseguida en la prueba (54,55).…”

Section: Efecto En El Rendimiento Deportivounclassified

“…Además, se ha observado que si los periodos de recuperación entre sprints son más cortos (menores de 30 segundos), el efecto de la suplementación es significativamente mayor, por una mayor acumulación de H +43 , que si los periodos de recuperación duran varios minutos (56). Sin embargo, parece que no se encuentran resultados positivos en test realizados con un ejercicio continuo llevados hasta el agotamiento (44,50), o de larga duración (57).…”

Section: Efecto En El Rendimiento Deportivounclassified

Ayudas ergogénicas en el deporte

Moriones¹,

Santos²

2017

Nutr Hosp

View full text Add to dashboard Cite

Introduction: Very few nutritional supplements have scientifi cally demonstrated their effectiveness as an ergogenic aid. This review will examine creatine monohydrate (MC), the β-hydroxy-β-methylbutyrate (HMB), sodium bicarbonate (BS), the β-alanine and caffeine. Objectives: To analyze the effi cacy, mechanisms of action, dose, side effects and some sports that can benefi t from their consumption. Methods: Searching in PubMed bibliographic database reviews from the last 15 years and original articles from the last 5 years of the studied substances. Results: Doses of 20 mg/day for 4-7 days are effective in improving strength and muscular power and performance in short and repeated sprints. HMB at doses of 3 g/day for at least 2 weeks contributes to increased lean mass and fat-free mass. The intake of 0.3 g/kg of BS improves performance on tests of 400-1,500 meters in athletics and intermittent sprints. Meanwhile, doses of 80 mg/kg/day of β-alanine for 4-10 weeks may improve performance in high-intensity intermittent exercise. Finally, caffeine at doses of 2 mg/kg improves responsiveness and 3-6 mg/kg improves performance in endurance tests. Conclusions: The revised supplements have shown their effi cacy in physical performance, but it is needed to keep in mind that most studies have been conducted with recreational-level athletes. Generally, the better the individual´s fi tness level is the less improvement in physical performance the supplement shows. However, an increase of only 1% may sometimes allow the athlete to advance several positions in a fi nal. Finally, we should draw attention to the importance of optimizing nutrition before considering the introduction of sports supplements, especially in children and youth. All analyzed substances have scientifi c basis supporting its ergogenic effect. All of them can be found in the market with Certifi cate of Quality and Purity.

show abstract

Effect of beta-alanine supplementation on the onset of blood lactate accumulation (OBLA) during treadmill running: Pre/post 2 treatment experimental design

Cited by 59 publications

References 39 publications

The effects of beta‐alanine supplementation on physical working capacity at heart rate threshold

The effects of beta‐alanine supplementation on physical working capacity at heart rate threshold

The Effect of 28 Days of Beta-alanine Supplementation on Exercise Capacity and Insulin Sensitivity in Individuals with Type 2 Diabetes Mellitus: A Randomised, Double-blind and Placebo-controlled Pilot Trial

Ayudas ergogénicas en el deporte

Contact Info

Product

Resources

About