Effect of Bezafibrate and Ginkgo biloba Extract Combination on Doxorubicin-Induced Cardiotoxicity in Rats
Asoo Nihad Abtar,
Zhwan Azad Abdalla,
Ahmed Azad Kareem
et al.
Abstract:Objectives: This study aimed to evaluate the possible synergistic effect of bezafibrate and ginkgo biloba (GKB) extract on cardiotoxicity induced by doxorubicin. Methods: Thirty rats were allocated into 5 groups: The negative control group was treated daily with 1 ml of distilled water orally by gavage tube; the positive control received doxorubicin 3.7 mg/kg on day 11 for 3 days intraperitoneally; the bezafibrate group received 100mg/kg orally by gavage tube; the GKB group received 60mg/kg orally by gavage tu… Show more
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