Effect of Bilateral Opercular Syndrome on Speech Perception

Walker, Grant M.; Rollo, Patrick S.; Tandon, Nitin; Hickok, Gregory

doi:10.1162/nol_a_00037

Cited by 1 publication

(1 citation statement)

References 70 publications

(75 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further additional support for this conclusion comes from a recent study of two cases of acquired opercular syndrome, both with complete anarthria secondary to bilateral removal of most of the inferior, posterior frontal cortex. Despite being completely unable to voluntarily control their vocal tracts, both individuals were able to comprehend words at ceiling levels (Walker, Rollo, Tandon, & Hickok, 2021).…”

Section: Discussionmentioning

confidence: 99%

The Neuroanatomy of Speech Processing: A Large-Scale Lesion Study

Rogalsky

Basilakos

Rorden

et al. 2020

Preprint

Self Cite

View full text Add to dashboard Cite

The neural basis of language has been studied for centuries, yet the networks critically involved in simply identifying or understanding a spoken word remain elusive. Several functional-anatomical models of the critical neural substrates of receptive speech processes have been proposed, including auditory-related regions in the (1) left mid-posterior superior temporal lobe, (2) left anterior superior temporal lobe, or (3) bilateral in the mid-posterior superior temporal areas, and (4) motor-related regions in the left frontal lobe (in normal and/or noisy conditions). One difficulty in comparing these models is that they often focus on different aspects of the sound-to-meaning pathway and different types of stimuli and tasks. Two auditory tasks that are typically used in separate studies-nonword discrimination and word comprehension-often yield different conclusions. We assessed word/nonword discrimination and clear/noisy word comprehension in 160 individuals with focal brain damage: left (n=115) or right (n=19) hemisphere stroke, left (n=18) or right (n=8) anterior temporal lobectomy, and 26 neurologically-intact controls. Discrimination and comprehension doubly dissociated both behaviorally and neurologically. In support of a bilateral model, clear speech comprehension was near ceiling in 92% of left stroke cases, and right temporal damage was, for the first time, found to impair phoneme discrimination. Lesion-symptom mapping analyses for the word discrimination, non-word discrimination, and noisy word comprehension tasks each implicated most of the left superior temporal gyrus (STG) except the anterior most regions. Comprehension tasks also implicated the left pMTG, while discrimination tasks also implicated more dorsal sensorimotor regions in posterior perisylvian cortex. 1 0Control Subjects. Twenty-six adults (21 female, age range = 42-83, mean age = 59 years, years of education range = 12-16, mean education = 15 years) were recruited and tested at San Diego State University. All control subjects were native English speakers, right-handed, and selfreported no history of psychological or neurological disease.Informed consent was obtained from each patient prior to participation in the study, and all procedures were approved by the Institutional Review Boards

show abstract

Section: Discussionmentioning

confidence: 99%