2007
DOI: 10.1016/j.transproceed.2007.01.065
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Effect of Bisphosphonates on Bone Mineral Density After Renal Transplantation as Assessed by Bone Mineral Densitometry

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Cited by 15 publications
(24 citation statements)
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“…We showed that parenteral pamidronate, a second-generation aminobisphosphonate, preserved BMD but was associated with development of adynamic bone disease. 3 Although there have been several prospective studies reporting the effects of parenteral 4,5 and oral bisphosphonates [6][7][8][9] on BMD, there are few studies in renal transplant patients using risedronate, a commonly used third-generation aminobisphosphonate, and its effect on BMD and biochemical measures. 10,11 There are no studies of serial histomorphometry in renal transplant recipients using risedronate.…”
mentioning
confidence: 99%
“…We showed that parenteral pamidronate, a second-generation aminobisphosphonate, preserved BMD but was associated with development of adynamic bone disease. 3 Although there have been several prospective studies reporting the effects of parenteral 4,5 and oral bisphosphonates [6][7][8][9] on BMD, there are few studies in renal transplant patients using risedronate, a commonly used third-generation aminobisphosphonate, and its effect on BMD and biochemical measures. 10,11 There are no studies of serial histomorphometry in renal transplant recipients using risedronate.…”
mentioning
confidence: 99%
“…Several previous studies have shown that bisphosphonates continued to improved bone mineral density after renal transplantation [7][9], [31], [32] and most of them showed the effect on both lumbar spine and femoral neck BMD. In a meta-analysis review of 1209 patients [33], treatment with bisphosphonates increased BMD in lumbar spine and femoral neck.…”
Section: Discussionmentioning
confidence: 92%
“…Further, osteopenia is defined as a condition in which the difference between the mean BMDs of the patients and healthy young adults is between 1 and 2.5 SDs [6]. Several studies have shown the beneficial effects of bisphosphonates on post-transplantation osteoporosis [7][9]. Other studies have shown that calcineurin inhibitors (CIs) have deleterious effects on bone mineral metabolism in rats [10][12], and that at least one cyclosporine has a protective effect on bone [13].…”
Section: Introductionmentioning
confidence: 99%
“…However, all pathologies associated with renal failure may not normalize even with good graft function. 1 Despite advances in patient and graft survivals after transplantation, persistent parathyroid and bone metabolic disorders are common complications. 2 Bone remodeling homeostasis is known to be defective.…”
mentioning
confidence: 99%