Unlike other crops, the jojoba shrub contains around 50% by weight of an almost odorless, colorless oil made mostly of monoesters of the straight-chain alcohols and acids, C20 and C22, with one double bond on either side. The shrub is distinct from other species. In order to create modified jojoba derivatives, scientists can modify both the olefinic group and the ester group of jojoba oil, which is detailed in this book chapter. Jojoba oil has been modified in studies for various uses. These alterations include isomerization, bromination, sulfur-chlorination, sulfurization, hydrogenation, epoxidation, hydroxymethylation, phosphonation, ethoxylation, Diels-Alder adduction, pinacol rearrangement, bonding with polyethylene, and boning with polystyrene matrix. The next paragraphs will cover all of the applications for these modified jojoba oil derivatives, including medicine, emulsifiers, detergents, surfactants, lubricating oil, lubricating oil additives, leather tanning, texture, and corrosion inhibitors.