can mimic short days, without causing inhibition of natural melatonin secretion, thus stimulating reproductive activity in sheep (Staples et al., 1992).
IntroductIonT he breeding season of ewe usually begins in the summer or early fall, in response to the shortening of the day length and ends during the late winter or early spring (Mura et al., 2014). The perception of light and dark alternation affects the epiphysis secretion of melatonin, with high levels secreted during night-hours and low levels during day light hours (Carcangiu et al., 2013). Thus, photoperiod is a major factor influencing reproductive activity in small ruminants (Bedos et al., 2014). Melatonin is a neuroendocrine signal that transduces information about the environmental light received by retina (El-Mokadem et al., 2017). The use of exogenous melatonin has received much attention across the globe to control reproductive activity (Abecia et al., 2011).