Effect of boron oxide addition on structural, thermal, in vitro bioactivity and antibacterial properties of bioactive glasses in the base S53P4 composition

Prasad, Sakthi; Datta, Susmit; Adarsh, Tarun; Diwan, Prerna; Annapurna, K.; Kundu, Biswanath; Biswas, Kaushik

doi:10.1016/j.jnoncrysol.2018.06.027

Cited by 49 publications

(35 citation statements)

References 47 publications

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“…Figure 9 Studies have shown that boron N 4 is considered to produce a strong effect on the overall glass structure such as network connectivity and higher glass transition temperature. 33,44 Consequently, it can be speculated that the introduction of B do not destroy the internal tetrahedral structure of silicate glass, which mutually verifies with the experimental structural analysis. Moreover, Figure 12 represents the partial simulative VDOS according to Equation (2) at 900 K from Fourier transformation, which reveals vibrational features.…”

Section: Aimd Simulationssupporting

confidence: 69%

“…43 It is also worth noting that the new absorption peak appeared at 1398 cm −1 for boron-containing MBGs is ascribed to the B-O stretching vibrations in [BO 3 ] units. 31,44 Moreover, the intensity of B-O tends to increase with the increasing boron amount. In addition, the absorption bands located at 1639 and 3460 cm −1 of all samples are assigned to OH groups, which may ascribe to the water absorbed from the environment.…”

Section: Characterization Of Mbgsmentioning

confidence: 97%

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Effect of B₂O₃ on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres

et al. 2021

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In this paper, the boron-containing mesoporous bioactive glass (MBG) nanospheres have been successfully synthesized by modified sol-gel method assisted by surfactant, and the effect of boron substitution on structure and bioactivity was evaluated by combining experiments and ab initio molecular dynamics (AIMD) simulations. All of the samples exhibit regularly uniform mesoporous spherical microstructure with an average size of about 60 nm, and the boron-containing MBGs show higher specific surface area with the value up to 416.20 m 2 /g. The simulated body fluid (SBF) immersion test confirms that the deposited hydroxyapatite (HA) evidently increases with the increasing of boron content, indicating that the biological behavior has been significantly improved resulting from incorporation of boron. Additionally, our results also reveal that B 2 O 3 substitution has positive impact on cell proliferation of human periodontal ligament cells (hPDLCs) at lower extracted concentration. Furthermore, AIMD simulation is employed to understand the relationship between structural changes and in vitro bioactivity in terms of structural information, especially the boron coordination number. The results illustrate that the boron-containing MBG nanospheres with excellent bioactivity are great potential for biomedical applications. K E Y W O R D Sab initio molecular dynamics, boron, cytotoxicity, mesoporous bioactive glass, sol-gel method How to cite this article: Bai N, Chen W, Luo L, et al. Effect of B 2 O 3 on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres.

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Section: Aimd Simulationssupporting

confidence: 69%

Section: Characterization Of Mbgsmentioning

confidence: 97%

Effect of B₂O₃ on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres

et al. 2021

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“…Research has revealed visible-light-induced antibacterial properties in boron-doped TiO2 [14][15][16]. However, in a previous study, boron-doped TiO2 was also found to exert a strong bactericidal effect in the dark [16].…”

Section: Analyses Of Boron-doped Titania Thin Filmsmentioning

confidence: 93%

Visible-Light-Responsive Antibacterial Property of Boron-Doped Titania Films

Wong

Sun

et al. 2020

Catalysts

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Pure titanium dioxide TiO2 photocatalytic substrates exhibit antibacterial activity only when they are irradiated with ultraviolet light, which comprises high-energy wavelengths that damage all life. Impurity doping of TiO2-related materials enables visible light to stimulate photocatalytic activity, which enhances opportunities for TiO2 to be used as a disinfectant in living environments. Boron-doped TiO2 displays visible-light-responsive bactericidal properties. However, because boron-derived compounds also exert notable antibacterial effects, most reports did not clearly demonstrate the extent to which the bactericidal property of boron-doped TiO2 is contributed by visible-light-stimulated photocatalysis. In addition, TiO2 thin films have considerable potential for applications in equipment that requires sterilization; however, the antibacterial properties of boron-doped TiO2 thin films have been examined by only a few studies. We found that boron-doped TiO2 thin films displayed visible-light-driven antibacterial properties. Moreover, because boron compounds may have intrinsic antibacterial properties, using control groups maintained in the dark, we clearly demonstrated that visible light stimulated the photocatalysis of boron-doped TiO2 thin films but not the residue boron compounds display antibacterial property. The bactericidal effects induced by visible light are equally potent for the elimination of the model organism Escherichia coli and human pathogens, such as Acinetobacter baumannii, Staphylococcus aureus, and Streptococcus pyogenes. The antibacterial applications of boron-doped TiO2 thin films are described, and relevant perspectives discussed.

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“…Another silicate BG that has received much attention is the 13–93 composition, which has shown less tendency to crystallize when sintered and is known to generate 3D scaffolds with superior mechanical properties [ 20 , 21 ]. Moreover, boron-containing BGs have demonstrated that boron addition into silicate BGs enhances the degradation rate [ 16 ], the process of apatite formation [ 22 , 23 ], antibacterial properties [ 23 ], osteogenesis [ 24 – 26 ], angiogenesis [ 26 – 28 ], and has also an effect on the BG mechanical strength [ 22 , 29 ]. Boron-doped BGs have been shown to be attractive materials for applications in soft and hard tissue engineering [ 15 , 30 ].…”

Section: Introductionmentioning

confidence: 99%

Bioactive glasses incorporating less-common ions to improve biological and physical properties

Pantulap

Arango‐Ospina

Boccaccını

2021

J Mater Sci: Mater Med

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Bioactive glasses (BGs) have been a focus of research for over five decades for several biomedical applications. Although their use in bone substitution and bone tissue regeneration has gained important attention, recent developments have also seen the expansion of BG applications to the field of soft tissue engineering. Hard and soft tissue repair therapies can benefit from the biological activity of metallic ions released from BGs. These metallic ions are incorporated in the BG network not only for their biological therapeutic effects but also in many cases for influencing the structure and processability of the glass and to impart extra functional properties. The “classical” elements in silicate BG compositions are silicon (Si), phosphorous (P), calcium (Ca), sodium (Na), and potassium (K). In addition, other well-recognized biologically active ions have been incorporated in BGs to provide osteogenic, angiogenic, anti-inflammatory, and antibacterial effects such as zinc (Zn), magnesium (Mg), silver (Ag), strontium (Sr), gallium (Ga), fluorine (F), iron (Fe), cobalt (Co), boron (B), lithium (Li), titanium (Ti), and copper (Cu). More recently, rare earth and other elements considered less common or, some of them, even “exotic” for biomedical applications, have found room as doping elements in BGs to enhance their biological and physical properties. For example, barium (Ba), bismuth (Bi), chlorine (Cl), chromium (Cr), dysprosium (Dy), europium (Eu), gadolinium (Gd), ytterbium (Yb), thulium (Tm), germanium (Ge), gold (Au), holmium (Ho), iodine (I), lanthanum (La), manganese (Mn), molybdenum (Mo), nickel (Ni), niobium (Nb), nitrogen (N), palladium (Pd), rubidium (Rb), samarium (Sm), selenium (Se), tantalum (Ta), tellurium (Te), terbium (Tb), erbium (Er), tin (Sn), tungsten (W), vanadium (V), yttrium (Y) as well as zirconium (Zr) have been included in BGs. These ions have been found to be particularly interesting for enhancing the biological performance of doped BGs in novel compositions for tissue repair (both hard and soft tissue) and for providing, in some cases, extra functionalities to the BG, for example fluorescence, luminescence, radiation shielding, anti-inflammatory, and antibacterial properties. This review summarizes the influence of incorporating such less-common elements in BGs with focus on tissue engineering applications, usually exploiting the bioactivity of the BG in combination with other functional properties imparted by the presence of the added elements.

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Effect of boron oxide addition on structural, thermal, in vitro bioactivity and antibacterial properties of bioactive glasses in the base S53P4 composition

Cited by 49 publications

References 47 publications

Effect of B₂O₃ on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres

Effect of B₂O₃ on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres

Visible-Light-Responsive Antibacterial Property of Boron-Doped Titania Films

Bioactive glasses incorporating less-common ions to improve biological and physical properties

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Effect of boron oxide addition on structural, thermal, in vitro bioactivity and antibacterial properties of bioactive glasses in the base S53P4 composition

Cited by 49 publications

References 47 publications

Effect of B2O3 on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres

Effect of B2O3 on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres

Visible-Light-Responsive Antibacterial Property of Boron-Doped Titania Films

Bioactive glasses incorporating less-common ions to improve biological and physical properties

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Product

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Effect of B₂O₃ on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres

Effect of B₂O₃ on the structural and in vitro biological assessment of mesoporous bioactive glass nanospheres