Effect of Bovine Colostrum Dietary Supplementation on Rabbit Meat Quality

Castrica, Marta; Menchetti, Laura; Agradi, Stella; Curone, Giulio; Vigo, D.; Pastorelli, G.; Giancamillo, A. Di; Modina, S.; Riva, Federica; Serra, Valentina; Miraglia, Dino; Andoni, Egon; Brecchia, Gabriele; Balzaretti, C.

doi:10.3390/foods11213433

Cited by 7 publications

(8 citation statements)

References 75 publications

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“…The animals used in the trial were suckled by mothers who were fed the same diet they received after weaning. These diets were previously used in another experiment [ 38 ].…”

Section: Methodsmentioning

confidence: 99%

“…With regards to rabbits, the effects of BC supplementation have been assessed on meat quality [ 38 ] and diarrhoea prevention at weaning [ 39 ], yet its action on the gut microbiota remains unexplored. Only recently, the bacterial microbiota composition along the gastrointestinal tract of rabbits has been characterized [ 40 , 41 ], and its changes after dietary supplementations have been considered [ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

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Bovine Colostrum Supplementation Modulates the Intestinal Microbial Community in Rabbits

Agradi

Cremonesi

Menchetti

et al. 2023

Animals

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BC is a nutraceutical that can modulate intestinal microbiota. This study investigates the effects of BC diet supplementation on luminal and mucosa-associated microbiota in the jejunum, caecum, and colon of rabbits. Twenty-one New Zealand White female rabbits were divided into three experimental groups (n = 7) receiving a commercial feed (CTRL group) and the same diet supplemented with 2.5% and 5% BC (2.5% BC and 5% BC groups, respectively), from 35 (weaning) to 90 days of age (slaughtering). At slaughter, the digestive tract was removed from each animal, then both content and mucosa-associated microbiota of jejunum, caecum, and colon were collected and analysed by Next Generation 16SrRNA Gene Sequencing. Significant differences were found in the microbial composition of the three groups (i.e., beta-diversity: p < 0.01), especially in the caecum and colon of the 2.5% BC group. The relative abundance analysis showed that the families most affected by the BC administration were Clostridia UCG-014, Barnesiellaceae, and Eggerthellaceae. A trend was also found for Lachnospiraceae, Akkermansiaceae, and Bacteroidaceae. A functional prediction has revealed several altered pathways in BC groups, with particular reference to amino acids and lactose metabolism. Firmicutes:Bacteroidetes ratio decreased in caecum luminal samples of the 2.5% BC group. These findings suggest that BC supplementation could positively affect the intestinal microbiota. However, further research is needed to establish the optimal administration dose.

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“…The animals used in the trial were suckled by mothers who were fed the same diet they received after weaning. These diets were previously used in another experiment [ 38 ].…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Bovine Colostrum Supplementation Modulates the Intestinal Microbial Community in Rabbits

Agradi

Cremonesi

Menchetti

et al. 2023

Animals

Self Cite

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“…Over the last few years, an increasing number of clinical trials have achieved significant results indicating bovine colostrum (BC) as a promising nutraceutical that can prevent or alleviate various diseases in humans and animals as well [13][14][15][16][17][18][19][20][21][22]. BC is the first biological fluid produced by the mammary gland of cows after calving in the first 4 days of lactation, before becoming mature milk [23].…”

Section: Introductionmentioning

confidence: 99%

Intestine Health and Barrier Function in Fattening Rabbits Fed Bovine Colostrum

Aidos,

Pallaoro,

Mirra

et al. 2023

Veterinary Sciences

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The permeability of the immature intestine is higher in newborns than in adults; a damaged gut barrier in young animals increases the susceptibility to digestive and infectious diseases later in life. It is therefore of major importance to avoid impairment of the intestinal barrier, specifically in a delicate phase of development, such as weaning. This study aimed to evaluate the effects of bovine colostrum supplementation on the intestinal barrier, such as the intestinal morphology and proliferation level and tight junctions expression (zonulin) and enteric nervous system (ENS) inflammation status (through the expression of PGP9.5 and GFAP) in fattening rabbits. Rabbits of 35 days of age were randomly divided into three groups (n = 13) based on the dietary administration: commercial feed (control group, CTR) and commercial feed supplemented with 2.5% and 5% bovine colostrum (BC1 and BC2 groups, respectively). Rabbits receiving the BC1 diet showed a tendency to have better duodenum morphology and higher proliferation rates (p < 0.001) than the control group. An evaluation of the zonulin expression showed that it was higher in the BC2 group, suggesting increased permeability, which was partially confirmed by the expression of GFAP. Our results suggest that adding 2.5% BC into the diet could be a good compromise between intestinal morphology and permeability, since rabbits fed the highest inclusion level of BC showed signs of higher intestinal permeability.

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“…The fecal microbiota and its functional capacity associated with weaning weight in meat rabbits [24], hygiene of the environment [25], season [15], and drug treatments [26,27] have been investigated. It was established that these factors influencing the microbiota composition can also affect the quality of the carcass and meat of the rabbit [28][29][30]. Actually, only a few studies evaluated the effect of the breeds and the growth rate on the microbiota composition [31].…”

Section: Introductionmentioning

confidence: 99%

Diversity and Co-Occurrence Pattern Analysis of Cecal and Jejunal Microbiota in Two Rabbit Breeds

Abdel-Kafy

Kamel

Morsy

et al. 2023

Animals

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This study aimed to evaluate the productive performance and microbiota variation in the jejunum and cecum of two rabbit breeds with different growth rates. This study was carried out on Native Middle-Egypt Breed (NMER) and Giant Flanders (GF) rabbits from 5 weeks to 12 weeks of age. Twenty NMER (NM) and GF male rabbits were slaughtered, and the jejunum and cecum tracts were collected to assay gut microbiota composition via 16S ribosomal RNA (rRNA) gene sequencing and histology examination. At 12 weeks of age, daily weight gain, villus height in the jejunum, total protein, and albumin were higher in GF rabbits than in NMER rabbits. Also, the jejunal villi of GF were well arranged in their dense borders. The microbiota between the jejunum and cecum was significantly different in terms of Beta-diversity. A significant correlation between Enterococcus (jejunum NM samples) and Lactobacillus (cecum GF samples) with body weight and weight gain was found (p < 0.05). Moreover, Escherichia-Shigella in the cecum of NM was significantly correlated with weight gain (p < 0.05). The most abundant genera identified in the jejunal and cecal contents of GF were generally beneficial microbiota. They may also play a role in reducing the pathogenic effects of Escherichia coli in these rabbits.

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Effect of Bovine Colostrum Dietary Supplementation on Rabbit Meat Quality

Cited by 7 publications

References 75 publications

Bovine Colostrum Supplementation Modulates the Intestinal Microbial Community in Rabbits

Bovine Colostrum Supplementation Modulates the Intestinal Microbial Community in Rabbits

Intestine Health and Barrier Function in Fattening Rabbits Fed Bovine Colostrum

Diversity and Co-Occurrence Pattern Analysis of Cecal and Jejunal Microbiota in Two Rabbit Breeds

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