Effect of caffeine on bladder function in patients with overactive bladder symptoms

Lohsiriwat, Supatra; Hirunsai, Muthita; Chaiyaprasithi, Bansithi

doi:10.4103/0974-7796.75862

Cited by 118 publications

(51 citation statements)

References 14 publications

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“…The fluid balance chart establishes patterns and type of fluid intake. The types of fluid taken is important especially those that may irritate the bladder such as caffeinated, carbonated or citrus drinks (Miller et al, 2016, Lohsiriwat., Hirunsai and Chaiyaprasithi, 2011and Maserejian et al, 2013 (Staskin et al 2009, NICE, 2015aand NICE, 2015b can help determine how the bladder dysfunction is affecting them individually.…”

Section: Assessmentmentioning

confidence: 99%

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An overview of urinary incontinence

Bardsley

2016

Practice Nursing

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Urinary incontinence is a common problem that is often under-reported due to the embarrassing nature and social stigma attached. Urinary incontinence can have a considerable effect on an individual's quality of life, but can be significantly improved with correct assessment, treatment and management. Conservative treatment options including: pelvic floor exercises, bladder retraining and fluid modification are recommended before referral to secondary services. This article provides an overview of the main types of urinary incontinence, and summarises recent guidelines for the assessment, diagnosis and effective conservative treatment options for them and when a referral for specialist care is required.

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Section: Assessmentmentioning

confidence: 99%

“…if it is too high or too low and caffeine restriction (Lohsiriwat, Hirunsai andChaiyaprasithi, 2011 andMaserejian et al, 2013).  Treatment of constipation  Advice to stop smoking  Advice about weight loss if their BMI is over 30 (Lucas et al 2015)  Bladder retraining including time delayed voiding.…”

Section: Treatment Optionsmentioning

confidence: 99%

An overview of urinary incontinence

Bardsley

2016

Practice Nursing

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“…Interestingly, BSM has all the enzymes required to convert ATP to adenosine, which is likely to be important because adenosine causes smooth muscle to relax. In this context, a number of studies have shown that caffeine can exacerbate lower urinary tract symptoms, including OAB (52)(53)(54). Although the mechanism remains unclear because caffeine has several cellular effects, it is known to inhibit adenosine receptors at the low doses found from drinking coffee and, thus, may inhibit detrusor relaxation (53).…”

Section: Detrusor Smooth Musclementioning

confidence: 99%

“…In this context, a number of studies have shown that caffeine can exacerbate lower urinary tract symptoms, including OAB (52)(53)(54). Although the mechanism remains unclear because caffeine has several cellular effects, it is known to inhibit adenosine receptors at the low doses found from drinking coffee and, thus, may inhibit detrusor relaxation (53). Intriguingly, purinergic signaling becomes more prominent in disease and in aging (55)(56)(57) and may emerge to play a dominant role in patients with partial outlet obstruction and interstitial cystitis, potentially accounting for up to 65% of the total contraction force (58).…”

Section: Detrusor Smooth Musclementioning

confidence: 99%

Control of Urinary Drainage and Voiding

Hill

2015

Clinical Journal of the American Society of Nephrology

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Urine differs greatly in ion and solute composition from plasma and contains harmful and noxious substances that must be stored for hours and then eliminated when it is socially convenient to do so. The urinary tract that handles this output is composed of a series of pressurizable muscular compartments separated by sphincteric structures. With neural input, these structures coordinate the delivery, collection, and, ultimately, expulsion of urine. Despite large osmotic and chemical gradients in this waste fluid, the bladder maintains a highly impermeable surface in the face of a physically demanding biomechanical environment, which mandates recurring cycles of surface area expansion and increased wall tension during filling, followed by rapid wall compression during voiding. Afferent neuronal inflow from mucosa and submucosa communicates sensory information about bladder fullness, and voiding is initiated consciously through coordinated central and spinal efferent outflow to the detrusor, trigonal internal sphincter, and external urethral sphincter after periods of relative quiescence. Provocative new findings suggest that in some cases, lower urinary tract symptoms, such as incontinence, urgency, frequency, overactivity, and pain may be viewed as a consequence of urothelial defects (either urothelial barrier breakdown or inappropriate signaling from urothelial cells to underlying sensory afferents and potentially interstitial cells). This review describes the physiologic and anatomic mechanisms by which urine is moved from the kidney to the bladder, stored, and then released. Relevant clinical examples of urinary tract dysfunction are also discussed.

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“…Regular caffeine consumers have been reported to exhibit symptoms of dependence (Striley et al 2011), and caffeine abstinence following habitual consumption has been associated with symptoms such as fatigue, difficulty concentrating and headaches (Juliano et al 2012). Caffeine is known to cause a mild diuresis (Riesenhuber et al 2006;Lohsiriwat et al 2011) which may result in increased urinary frequency and may also affect detrusor stability (Creighton and Stanton 1990). Higher caffeine intakes have been associated with urinary incontinence (UI) (Gleason et al 2013) and caffeine intake has been associated with OAB.…”

Section: Introductionmentioning

confidence: 99%