Effect of Calcium Channel Blockers on Baroreceptor Reflex in Anaesthetized Cats

To gain information about the genetic basis of a complex disease such as hypertension, blood pressure averages are often obtained and used as phenotypes in genetic mapping studies. In contrast, direct measurements of physiological regulatory mechanisms are not often obtained, due in large part to the time and expense required. As a result, little information about the genetic basis of physiological controlling mechanisms is available. Such information is important for disease diagnosis and treatment. In this article, we use a mathematical model of blood pressure to derive phenotypes related to the baroreceptor reflex, a short-term controller of blood pressure. The phenotypes are then used in a quantitative trait loci (QTL) mapping study to identify a potential genetic basis of this controller.

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Effect of T- and L-Type Calcium Channel Blockers on Pulmonary Microhemodynamics in a Rabbit Model of Pulmonary Thromboembolism

Evlakhov

Poyassov

Berezina

2023

J Evol Biochem Phys

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Effect of Calcium Channel Blockers on Baroreceptor Reflex in Anaesthetized Cats

Cited by 4 publications

References 13 publications

Pulmonary Microcirculation in Experimental Model of Pulmonary Thromboembolism after Pretreatment with Chloroquine

Pulmonary Microcirculation in Experimental Model of Pulmonary Thromboembolism after Pretreatment with Chloroquine

Mapping Baroreceptor Function to Genome: A Mathematical Modeling Approach

Effect of T- and L-Type Calcium Channel Blockers on Pulmonary Microhemodynamics in a Rabbit Model of Pulmonary Thromboembolism

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