Effect of carbonaceous ultrafine particles on the structure and oligomerization of Aβ42 peptide

Kaumbekova, Samal; Torkmahalleh, Mehdi Amouei; Umezawa, Masakazu; Wang, Yanwei; Shah, Dhawal

doi:10.1016/j.envpol.2023.121273

Cited by 3 publications

(1 citation statement)

References 45 publications

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“…[57] Quit recently, malic acid-based DESs were analyzed by varying the amount of water to study the conformational stability of IA. [58] The findings revealed that insulin exhibits stronger stabilization in DESs, and its diluted form compared to water-based alternatives. They further analyzed that the insulin dimer is stable in the DES with low water content, however, in the presence of higher amounts of water, it is destabilized, and the monomers are separated (Table 1; entries 2-5).…”

Section: Overview Of Designer Solvents On the Stability Of Insulinmentioning

confidence: 98%

Designer Solvents for Pharmaceutics: Role of Ionic Liquids/ Deep Eutectic Solvents in Pharmaceutical Formulations

Dhiman,

Alhammadi,

Kim

et al. 2024

Advanced Therapeutics

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The design of biologic and synthetic drugs in the pharmaceutical industry is facing three key challenges, namely, ensuring bioavailability, solubility, and stability. Ionic liquids (ILs) and deep eutectic solvents (DESs), classified as designer solvents, have emerged as excellent solvents for improving the permeability and stability of biotherapeutic drugs. Moreover, they have shown remarkable solubilizing effects for synthetic drugs, particularly in solubilizing active pharmaceutical ingredients (API), and are known as eco‐friendly solvents. Thus, in this review, the development of designer formulations in pharmaceutical industries is reported, and the underlying strategies for designing the most efficient formulations for both biotherapeutics and synthetic drugs are examined.

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Section: Overview Of Designer Solvents On the Stability Of Insulinmentioning

confidence: 98%

Designer Solvents for Pharmaceutics: Role of Ionic Liquids/ Deep Eutectic Solvents in Pharmaceutical Formulations

Dhiman,

Alhammadi,

Kim

et al. 2024

Advanced Therapeutics

View full text Add to dashboard Cite

show abstract

Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells – Implications for Alzheimer's disease

Mussalo,

Lampinen,

Avesani

et al. 2024

Redox Biology

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Characterization of risks and pathogenesis of respiratory diseases caused by rural atmospheric PM2.5

Zhang,

Li,

et al. 2024

Science of The Total Environment

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Effect of carbonaceous ultrafine particles on the structure and oligomerization of Aβ42 peptide

Cited by 3 publications

References 45 publications

Designer Solvents for Pharmaceutics: Role of Ionic Liquids/ Deep Eutectic Solvents in Pharmaceutical Formulations

Designer Solvents for Pharmaceutics: Role of Ionic Liquids/ Deep Eutectic Solvents in Pharmaceutical Formulations

Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells – Implications for Alzheimer's disease

Characterization of risks and pathogenesis of respiratory diseases caused by rural atmospheric PM2.5

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