2020
DOI: 10.1055/s-0040-1721234
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Effect of Carbonate Apatite Hydrogel-Advanced Platelet-Rich Fibrin Injection on Osteoblastogenesis during Orthodontic Relapse in Rabbits

Abstract: Objective The study aimed to determine the effect of carbonate apatite (CHA) hydrogel-aPRF on osteoblastogenesis during relapse in rabbits. Materials and Methods Forty-five rabbits were divided into three groups (n = 15): the control, CHA, and CHA-autologous platelet-rich fibrin (aPRF) groups. An open-coil spring was compressed between brackets to distalize the lower incisors of the rabbits by delivering a force of 50 cN for 1 week. The new position of the teeth was retained for 14 days, and CHA hydrogel-aPRF … Show more

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Cited by 10 publications
(37 citation statements)
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“…Eight articles in experimental animal models were included; four studies were conducted on rats [20][21][22][23], two used rabbits [24,25], one study was conducted on mice [26] and one study on guinea pigs [27], as shown in Table 1. A quality assessment was performed according to the ARRIVE guidelines [18].…”
Section: Selection Of Studiesmentioning
confidence: 99%
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“…Eight articles in experimental animal models were included; four studies were conducted on rats [20][21][22][23], two used rabbits [24,25], one study was conducted on mice [26] and one study on guinea pigs [27], as shown in Table 1. A quality assessment was performed according to the ARRIVE guidelines [18].…”
Section: Selection Of Studiesmentioning
confidence: 99%
“…All studies used a hydrogel of different polymer-gelatin-based composition [20,[24][25][26][27], chitosan hydrogel [20], polyethylene glycol-polycaprolactone-polyethylene glycol [21], hydroxyethyl cellulose [22], methylcellulose [23] for delivery of active substances: carbonated hydroxyapatite [24,25], curcumin [20], sclerostin [21], a formulation of RANKL [22], risedronate bisphosphonate [27], epigallocatechin [26] and parathyroid hormone [23], to accelerate orthodontic tooth movement or inhibit the post treatment relapse. Tooth movement was measured with a digital vernier or in the tomographic software depending on each article.…”
Section: General Characteristics Of the Studiesmentioning
confidence: 99%
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