Effect of cardiac glycosides from Nerium indicum on feeding rate, digestive enzymes activity and ultrastructural alterations of hepatopancreas in Pomacea canaliculata

Dai, Ling-Peng; Xiaowei, Qian; Nan, Xuyang; Zhang, Yejian

doi:10.1016/j.etap.2013.11.012

Cited by 9 publications

(5 citation statements)

References 48 publications

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“…Glycogen is the primary and intermediate source of energy. The cardiac glycosides of N. indicum decreased acetylcholinesterase (AChE) activities and impaired the hepatopancreas tissues of P. canaliculate, resulting in the fatal inhibition of the activity of digestive enzymes as well as the feeding rate [39,45]. Nicotine acts by mimicking acetylcholine and it exerts a toxic effect in both vertebrates and invertebrates as a neurotoxin by binding to nicotinic acetylcholine receptors and inhibiting their penetration into the synapse [46].…”

Section: Discussionmentioning

confidence: 99%

Development and Evaluation of Poly Herbal Molluscicidal Extracts for Control of Apple Snail (Pomacea maculata)

2017

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Golden Apple Snail (GAS) is the most destructive invasive rice pest in Southeast Asia. The cost of synthetic molluscicides, their toxicity to non-target organisms, and their persistence in the environment have propelled the research of plant-derived molluscicides. Most research efforts have focused on individual plant extracts for their molluscicidal potency against GAS and have not been proven to be entirely effective in rice field conditions. Selective combination of synergistically acting molluscicidal compounds from various plant extracts might be an effective alternative. In this direction, ethanolic extracts from six different plants (Neem, Tobacco, Nerium, Pongamia, Zinger, and Piper) were evaluated against Pomacea maculata Perry. Of the various combinations studied, a binary extract (1:1) of nerium and tobacco (LC 90 177.71 mg/L, 48 h), and two tri-herbal extract formulations (1:1:1) of (nerium + tobacco + piper) and (nerium + tobacco + neem) were found to be most effective, with LC 90 values of 180.35 mg/L and 191.52 mg/L, respectively, in laboratory conditions. The synergistic effect of combined herbal extracts resulted in significant reduction in LC 90 values of the individual extracts. The findings of this study demonstrate that the selective combinations of potent molluscicidal herbal extracts are effective for management of P. maculata under laboratory conditions.

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Section: Discussionmentioning

confidence: 99%

Development and Evaluation of Poly Herbal Molluscicidal Extracts for Control of Apple Snail (Pomacea maculata)

2017

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“…Protein was reported to serve as an alternate source of energy under extreme stress conditions (Suryavanshi et al, 2009). Stimulation the activity of trypsin may be an adaptive response of D. magna to extreme conditions (Dai et al, 2014). There was no signi cant difference in trypsin activities between Group M-H, CTP and Mix-H and control group (p > 0.05).…”

Section: Enzyme Activitymentioning

confidence: 95%

Combined Toxicity and Toxicity Persistence of Antidepressants Citalopram and Mirtazapine to Zooplankton Daphnia Magna

Ma¹,

Li²,

Wei³

et al. 2021

Preprint

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Citalopram (CTP) and mirtazapine (MTP) are two typical psychoactive drugs used for the treatment of depression. As emerging pollutants, CTP and MTP are of widely concern because they are active substances for organisms. However, the studies about the toxicity potential of CTP/MTP pollution to aquatic organisms were limited. In the present study, the effects of CTP and MTP on the feeding behavior, heartbeat, nutritional enzymes and related gene expressions of Daphnia magna were investigated under single and mixed environmental stress. Meanwhile, the recovery of exposed D. magna was studied to analyze the toxic persistence of those pollutants. After 24 h of exposure, the ingestion rate decreased significantly under 1.45 mg/L of CTP. In the mixed treatment groups, no significant synergistic effect of CTM and MTP on daphnia’ feeding inhibition was found. After 24 h of recovery, the feeding behavior of D. magna was stimulated by compensatory stimulation. At exposure period, the heartbeat rate of exposed D. magna increased significantly, and was recovered during the recovery period. The activity of α-amylase (AMS) and trypsin, and their relative gene expression were significantly changed in most of the exposed daphnia, both in the exposure period and recovery period. But there were different responses between gene transcription with enzyme activity. In general, psychoactive drugs have an obvious toxic threat to aquatic organisms, and after acute exposure, the physiological function of D. magna could be recovered to a certain extent. The results were helpful to evaluate the ecological risk of psychotropic drugs in aquatic environments.

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“…Protein was reported to serve as an alternate source of energy under extreme stress conditions (Suryavanshi et al, 2009). Stimulating the activity of trypsin may be an adaptive response of D. magna to extreme conditions (Dai et al, 2014). There was no signi cant difference in trypsin activities between Group M-H, CTP and Mix-H and control group (p > 0.05).…”

Section: Enzyme Activitymentioning

confidence: 95%

Combined Toxicity and Toxicity Persistence of Antidepressants Citalopram and Mirtazapine to Zooplankton Daphnia Magna

Dong

et al. 2021

Preprint

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Citalopram (CTP) and mirtazapine (MTP) are two typical psychoactive drugs used for the depression treatment. As emerging pollutants, CTP and MTP has been given widely concern because they are active substances for organisms. Therefore, the ecotoxicological risks of aquatic organisms should be paid more attention to. In this study, the effects of CTP and MTP on the feeding behavior, heartbeat, nutritional enzymes and related gene transcriptions of Daphnia magna were investigated under single and mixed environmental stress. Meanwhile, the recovery of exposed D. magna was studied to analyze the toxic persistence of those pollutants. After 24-hexposure, the ingestion rate decreased by 34.2% and 21.5%, in the group of C-H and Mix-H respectively. After 24-h recovery, the feeding behavior of D. magna was stimulated by compensatory stimulation. In exposure period, the heartbeat rate of D. magna increased by 132.3%, 69%, 111.9%, 139.4%, and 92.4%, in the group of C-L, C-H, M-L, M-H and Mix-L respectively, and was recovered during the recovery period. The activity of α-amylase (AMS) and trypsin were significantly changed in most of the exposed daphnia, both in the exposure period and recovery period. CTP/MTP exposure stimulated transcription of the α-amylase gene. M-H and Mix-H exposure inhibited transcription of the trypsin gene and other stimulated transcriptions. After 24-h recovery, the stimulative or inhibitory effects were alleviated. There were different responses between gene transcription and enzyme activity. In conclusion, our results highlighted the toxic effects of single and mixed pollution of CTP and MTP on feeding, heartbeat, enzymes and genes of D. magna.

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Effect of cardiac glycosides from Nerium indicum on feeding rate, digestive enzymes activity and ultrastructural alterations of hepatopancreas in Pomacea canaliculata

Cited by 9 publications

References 48 publications

Development and Evaluation of Poly Herbal Molluscicidal Extracts for Control of Apple Snail (Pomacea maculata)

Development and Evaluation of Poly Herbal Molluscicidal Extracts for Control of Apple Snail (Pomacea maculata)

Combined Toxicity and Toxicity Persistence of Antidepressants Citalopram and Mirtazapine to Zooplankton Daphnia Magna

Combined Toxicity and Toxicity Persistence of Antidepressants Citalopram and Mirtazapine to Zooplankton Daphnia Magna

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