Effect of Cardiac Surgery on One-Year Patient-Reported Outcomes: A Prospective Cohort Study

Charles, Eric J.; Mehaffey, J. Hunter; Hawkins, Robert B.; Green, China J.; Craddock, Ashley; Tyerman, Zachary; Larson, Nathaniel D.; Krön, Irving L.; Ailawadi, Gorav; Kozower, Benjamin D.

doi:10.1016/j.athoracsur.2020.09.061

Cited by 6 publications

(2 citation statements)

References 21 publications

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“…Prior to surgery, many patients have deconditioned physical function, related to cardiac-specific symptoms such as angina on exertion, and increased levels of fatigue, which they hope cardiac surgery will improve. 40 Angina relief is central to patient decision making around consenting to both percutaneous or surgical coronary interventions. 41 In the hope of resolving angina, patients frequently overestimate the benefits of cardiac intervention and underestimate the risks (e.g.…”

Section: Relationship Between Pro Domains and Outcomes In Cardiac Trialsmentioning

confidence: 99%

Patient-Reported Outcomes in Cardiovascular Trials

Creber

Spadaccio

Dimagli

et al. 2021

Canadian Journal of Cardiology

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Patient-reported outcomes (PROs) are reports of a person's health status that provide a global perspective of patient well-being. PROs can be classified into four primary domains: global, mental, physical, and social health. In this descriptive review, we focus on how PROs can be used in cardiac clinical trials, with an emphasis on cardiac surgical trials for patients with coronary heart disease and heart failure. We also highlight ongoing challenges and provide specific suggestions and novel opportunities to advance the field of cardiac clinical trials. Current challenges include the long-term measurement of PROs in clinical trials beyond one year, inconsistency in the choice of the outcome measures among studies, and the lack of measurement of PROs across multiple domains. Opportunities for advancement include measuring PROs using consumer health informatics tools, including returning information back to participants in formats that they can understand using visualization. Future opportunities include quantifying cohort specific minimally clinically important differences for PROs.

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Section: Relationship Between Pro Domains and Outcomes In Cardiac Trialsmentioning

confidence: 99%

Patient-Reported Outcomes in Cardiovascular Trials

Creber

Spadaccio

Dimagli

et al. 2021

Canadian Journal of Cardiology

View full text Add to dashboard Cite

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“…For example, to improve health-related (HR) QOL, thoracic surgeons have attempted to establish less painful and less invasive surgical approaches such as video-assisted thoracoscopic surgery (VATS; Gonzalez et al, 2022 ). However, the results of studies on postoperative HRQOL are less consistent ( Stamatis et al, 2019 ; Charles et al, 2021 ; Smolock et al, 2022 ), and controlling for postoperative HRQOL appears to be an extremely difficult task.…”

Section: Introductionmentioning

confidence: 99%

Preoperative state anxiety predicts postoperative health-related quality of life: A prospective observational study on patients undergoing lung cancer surgery

et al. 2023

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ObjectiveImproving quality of life (QOL) after surgery is very important. Recently, preoperative anxiety has been suggested to predict postoperative health-related (HR) QOL, however the accuracy of anxiety measurement remains problematic. We examined the relationship between preoperative anxiety level and postoperative HRQOL using qualitative and quantitative assessment of anxiety.MethodWe used a detailed anxiety assessment to quantitatively investigate preoperative anxiety as a predictor of postoperative HRQOL in lung cancer patients. Fifty one patients who underwent surgery for lung cancer were included. They were assessed four times: on admission, on discharge, 1 month after surgery, and 3 months after surgery. Anxiety was measured separately as “state anxiety” and “trait anxiety” using the State–Trait Anxiety Inventory, and HRQOL was measured using the EuroQol 5 dimension 5-level.ResultsThe HRQOL decreased at discharge and gradually recovered over time, reaching the same level at 3 months after surgery as at admission. HRQOL score was lower at discharge than at pre-surgery and 3 months after the surgery (p < 0.0001 each), and the score at 1 month after the surgery was lower than at pre-surgery (p = 0.007). In addition, multiple regression analysis showed that HRQOL at discharge was associated with “state anxiety” rather than “trait anxiety” at admission (p = 0.004).ConclusionThis study identifies the types of anxiety that affect postoperative HRQOL. We suggest that postoperative HRQOL on discharge may be improved by interventions such as psychological or medication treatment for preoperative state anxiety if identified preoperative state anxiety can be managed appropriately.

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