“…8 Simultaneously, a key chemical manufacturer, 3 M, has committed to cease production of HFE-7100 by the end of 2025. Solstice® PF (trans-1chloro-3,3,3-trifluoropropene) (GWP: 1) has been proposed as an alternative to HFE-7100; [9][10][11][12] however, this solvent has triggered operational concerns linked to its low boiling point of 19 °C, which is problematic for transport and use in warmer climates. This has led to renewed efforts to identify alternatives to replace HFE-7100, but the bridging solutions are heptane and petroleum ether, 13 each of which is flammable and toxic.…”