Effect of cellooligosaccharide or synbiotic feeding on growth performance, fecal condition and hormone concentrations in Holstein calves

Hasunuma, Toshiya; Kawashima, Kenji; Nakayama, Hirofumi; Murakami, Tasuku; Kanagawa, Hiroyuki; Ishii, Takashige; Akiyama, Kiyoshi; Yasuda, Kenji; Terada, Fuminori; Kushibiki, Shiro

doi:10.1111/j.1740-0929.2010.00861.x

Cited by 55 publications

(37 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A previous in vivo study (Hasunuma et al . ) showed that CE feeding improved ADG and feed efficiency in calves during the post‐weaning period, mainly due to enhanced production of short‐chain fatty acids by rumen microbiota. Stimulation of the intestinal flora in calves may further improve growth performance at an older age.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Effects of supplementation with cellooligosaccharides on growth performance of weaned calves on pasture

Kido

Tejima

Nagayama

et al. 2015

Animal Science Journal

Self Cite

View full text Add to dashboard Cite

We conducted two feeding experiments to evaluate the effects of cellooligosaccharide (CE) supplementation on growth performance in grazing beef calves. Calf sex and age and duration of the experimental period differed between the experiments. Experiment 1 (10 weeks) used 5.6-month-old castrated males; Experiment 2 (13 weeks) used 3.9-month-old females. Eight Japanese Black calves were assigned to either a control group (CON) or an experimental group (CE) fed CE at a rate of 10 g/day mixed with concentrate. Calves were stocked in fields in which Kentucky bluegrass was dominant. In both experiments, average daily gain tended to be greater in CE than in CON, especially in late stages of experiments, but no significant differences in body weight changes were observed. In Experiment 2, final heart girth was larger in CE than in CON calves. We monitored rumen microbial community composition in Experiment 2 and found increases in fibrolytic bacteria and methanogenic archaea in CE calves, but the overall microbial composition did not differ between the groups. Our results suggest that supplementation with CE may positively affect growth performance in weaned calves on pasture, but longer-term CE supplementation may be required to exhibit the effect.

show abstract

Section: Resultsmentioning

confidence: 99%

“…In addition, we have observed that CE is effective when provided to weaned calves, possibly as a result of improved rumen function (Hasunuma et al . ). Improving the ability of weaned calves to digest forage may be an ideal method for increasing weight gain.…”

Section: Introductionmentioning

confidence: 97%

Effects of supplementation with cellooligosaccharides on growth performance of weaned calves on pasture

Kido

Tejima

Nagayama

et al. 2015

Animal Science Journal

Self Cite

View full text Add to dashboard Cite

show abstract

“…A low‐concentration dose of cello‐oligosaccharides to plant elicits an immune response and increases resistance towards diseases . Animal studies have shown that adding cello‐oligosaccharides to the feed of calves causes fewer incidences of gastrointestinal infections and reduces the use of antibiotics . Cello‐oligosaccharides also have the potential to act as a non‐digestible prebiotic that can reduce the risk of lifestyle diseases in humans by promoting the growth of beneficial bacteria and inhibiting pathogenic bacterial species in the gastrointestinal tract .…”

Section: Figurementioning

confidence: 99%

“…[2] Animals tudies have shown that adding cello-oligosaccharides to the feed of calves causes fewer incidences of gastrointestinal infections and reduces the use of antibiotics. [3] Cello-oligosaccharides also have the potentialt oa ct as an ondigestible prebiotic that can reduce the risk of lifestylediseases in humansb yp romoting the growth of beneficial bacteria and inhibiting pathogenic bacterial speciesi nt he gastrointestinal tract. [1b, 4] Thus, cello-oligosaccharides can provide multiple benefits to the agriculturala nd healthcare industries.…”

mentioning

confidence: 99%

Soluble Cello‐Oligosaccharides Produced by Carbon‐Catalyzed Hydrolysis of Cellulose

2019

View full text Add to dashboard Cite

Cello‐oligosaccharides are biologically important molecules that can elicit a defensive immune response in plants and improve the health of animals. Cellulose, a polymer of glucose linked by β‐1,4‐glycosidic bonds, is an ideal feedstock for synthesis of cello‐oligosaccharides. However, cello‐oligosaccharides rapidly degrade under the conditions used for cellulose hydrolysis. Here, cellulose was hydrolyzed over a carbon catalyst in a semi‐flow reactor to achieve a high yield of cello‐oligosaccharides (72 %). The excellent activity of the oxidized carbon catalyst, the adsorption of cellulose on the catalyst, and the high space velocity of products in the reactor were essential. Moreover, a method for quantification of individual cello‐oligosaccharides was developed, which suggested a reduction in the rate of hydrolysis with a reduction in chain length.

show abstract

“…TNF-α and other cytokines activate NFκB, a transcription regulator that is activated by various intra and extra cellular stimuli. TNF-α induced inflammatory responses in cattle has been well documented 6,7. To further investigate the potential role of α-tocopherol in maintaining immuno-homeostasis in bovine cells, we undertook in vitro experiments using recombinant TNF-α as an immuno-stimulant to imitate inflammation response in cells with or without α-tocopherol pre-treatment.…”

Section: Introductionmentioning

confidence: 99%

Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells¹

Li¹,

Li²,

Kahl³

et al. 2011

Gene�Regul Syst Bio

View full text Add to dashboard Cite

To further investigate the potential role of α-tocopherol in maintaining immuno-homeostasis in bovine cells (Madin-Darby bovine kidney epithelial cell line), we undertook in vitro experiments using recombinant TNF-α as an immuno-stimulant to simulate inflammation response in cells with or without α-tocopherol pre-treatment. Using microarray global-profiling and IPA (Ingenuity Pathways Analysis, Ingenuity® Systems, http://www.ingenuity.com) data analysis on TNF-α-induced gene perturbation in those cells, we focused on determining whether α-tocopherol treatment of normal bovine cells in a standard cell culture condition can modify cell’s immune response induced by TNF-α challenge. When three datasets were filtered and compared using IPA, there were a total of 1750 genes in all three datasets for comparison, 97 genes were common in all three sets; 615 genes were common in at least two datasets; there were 261 genes unique in TNF-α challenge, 399 genes were unique in α-tocopherol treatment, and 378 genes were unique in the α-tocopherol plus TNF-α treatment. TNF-α challenge induced significant change in gene expression. Many of those genes induced by TNF-α are related to the cells immune and inflammatory responses. The results of IPA data analysis showed that α-tocopherol-pretreatment of cells modulated cell’s response to TNF-α challenge. In most of the canonical pathways, α-tocopherol pretreatment showed the antagonistic effect against the TNF-α-induced pro-inflammatory responses. We concluded that α-tocopherol pre-treatment has a significant antagonistic effect that modulates the cell’s response to the TNF-α challenge by altering the gene expression activities of some important signaling molecules.

show abstract

Effect of cellooligosaccharide or synbiotic feeding on growth performance, fecal condition and hormone concentrations in Holstein calves

Cited by 55 publications

References 26 publications

Effects of supplementation with cellooligosaccharides on growth performance of weaned calves on pasture

Effects of supplementation with cellooligosaccharides on growth performance of weaned calves on pasture

Soluble Cello‐Oligosaccharides Produced by Carbon‐Catalyzed Hydrolysis of Cellulose

Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells¹

Contact Info

Product

Resources

About

Effect of cellooligosaccharide or synbiotic feeding on growth performance, fecal condition and hormone concentrations in Holstein calves

Cited by 55 publications

References 26 publications

Effects of supplementation with cellooligosaccharides on growth performance of weaned calves on pasture

Effects of supplementation with cellooligosaccharides on growth performance of weaned calves on pasture

Soluble Cello‐Oligosaccharides Produced by Carbon‐Catalyzed Hydrolysis of Cellulose

Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells1

Contact Info

Product

Resources

About

Alpha-Tocopherol Alters Transcription Activities that Modulates Tumor Necrosis Factor Alpha (TNF-α) Induced Inflammatory Response in Bovine Cells¹