Effect of cerebrospinal fluid shunt surgery on lower urinary tract dysfunction in idiopathic normal pressure hydrocephalus

Abstract

iNPH is often associated with LUTS and both storage and voiding dysfunctions. CSF shunt surgery improved LUTS and storage dysfunction, with limited effects on voiding dysfunction.

Underactive Bladder and Detrusor Underactivity: New Advances and Prospectives

“…In addition to these prevalent and acknowledged neurogenic causes, there exist several unusual neurological conditions that could also be contributing to the development of DU, including inflammatory encephalomyelopathy [31], spinocerebellar ataxias (SCAs) [32], Charcot-Marie-Tooth disease (CMT) [33], neuromyelitis optica spectrum disorders (NMOSDs) [34], hereditary spastic paraplegia (HSP) [35], lumbar spinal stenosis [36], idiopathic normal pressure hydrocephalus (iNPH) [37], myelomeningocele (MMC) [38], closed spinal dysraphism (CSD) [39], and Friedreich's ataxia [40]. Certain neuroviruses, including zoster virus [41] and herpes simplex virus (HSV) [42], may also contribute to the development of UAB.…”

MRI diffusion and perfusion alterations in the mesencephalon and pons as markers of disease and symptom reversibility in idiopathic normal pressure hydrocephalus

“…Interestingly, core parts of the symptomatology in iNPH including disturbances in gait and postural control, cerebellar dystaxia, paratonia, impaired wakefulness and urinary urgency or incontinence, could represent dysfunction in systems neuroanatomically located in the mesencephalon and pons including the pedunculopontine nucleus in the mesencephalic tegmentum and the pontine micturition center [16][17][18]. So far, only a few radiological studies focusing on these regions have been performed [4,9,15,[19][20][21][22][23][24][25]. Results are inconsistent regarding morphological changes [21][22][23], and also from the few studies using diffusion and perfusion imaging techniques [9,24].…”