2021
DOI: 10.1590/s1980-220x2019008003680
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Effect of Chahuang ointment on prevention of phlebitis from peripherally inserted central catheter: randomized clinical trial

Abstract: Objective: To assess the effect of Chahuang ointment, a Chinese herbal ointment, on the prevention of phlebitis in patients with peripherally inserted central catheters. Method: This was a multicenter randomized controlled trial, with 171 eligible patients randomly assigned into one of three groups: the Chahuang ointment group, the Mucopolysaccharide Polysulfate cream group, and the control group. The degrees of vein injuries at 72 hours after peripherally inserted central catheter insertion were the primary … Show more

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Cited by 6 publications
(6 citation statements)
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“…Only a few mild skin inflammatory reactions were reported in the MPS cream groups, such as erythema, burning, and tingling at the application site. Many clinical trials also had the same results that no systematic AEs were related to the MPS cream (46,47). With regard to the incidence of skin inflammatory reactions, MPS cream was comparable to vaseline ointment and was superior to urea cream.…”
Section: Discussionmentioning
confidence: 74%
“…Only a few mild skin inflammatory reactions were reported in the MPS cream groups, such as erythema, burning, and tingling at the application site. Many clinical trials also had the same results that no systematic AEs were related to the MPS cream (46,47). With regard to the incidence of skin inflammatory reactions, MPS cream was comparable to vaseline ointment and was superior to urea cream.…”
Section: Discussionmentioning
confidence: 74%
“…Dari sekian banyak jenis infeksi nosokomial, Plebitis menempati peringkat pertama dibanding dengan infeksi lainnya. Plebhitis salah satu dampak pemberian terapi intravena, dampak lain yang dapat lebih lanjut ekxtravasasi, infiltrasi nekrosis, sampai bloodstream infectie (Wang et al, 2021).…”
Section: Pendahuluanunclassified
“…1,[3][4][5] The routine treatments for phlebitis, such as the external application of magnesium sulfate or mucopolysaccharide polysulfate cream, are unsatisfactory. [6][7][8] Therefore, developing new strategies for the prevention and treatment of phlebitis caused by intravenous infusion is needed. Potato glycoalkaloids, the naturally occurring steroidal glycoalkaloids, are well known for their toxicity and antimicrobial activity.…”
Section: Introductionmentioning
confidence: 99%