Effect of Chinese herbal medicine on lung disease: an updated review

Kumar, Virendra; Kumar, Davinder; Khatri, Naveen; Kumar, Ashwani; Khurana, Joginder

doi:10.53388/2022522027

Cited by 2 publications

(3 citation statements)

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“…Traditional Chinese herbal medicines have broad antitumor activity. 34,35 Pinostrobin inhibits many types of cancers, such as HT-29, HeLa, A549, and PC-3 cancer cells. 9,[36][37][38][39] Molecular docking analysis showed that pinostrobin strongly bound to a variety of cancer-promoting molecules, such as epidermal growth factor receptor (EGFR), tyrosine-protein kinase (JAK-2), mitogen-activated protein kinase kinase 4 (MKK4), vascular endothelial growth factor (VEGF), and DNA topoisomerase I (TOP1).…”

Section: Anticancer Effectsmentioning

confidence: 99%

Research Progress on the Pharmacological Effects and Molecular Mechanisms of Pinostrobin

Wang,

Zhao,

Chen

et al. 2023

Natural Product Communications

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Pinostrobin (5-hydroxy-7-methoxyflavanone) is an active flavonoid substance. It is widely present in many traditional Chinese herbs, including Carya cathayensis leaves, Boesenbergia rotunda and propolis. Pinostrobin possesses many pharmacological activities without significant toxicity. In addition to anti-inflammatory and antioxidant effects, pinostrobin also exerts antitumor effects. Pinostrobin is able to protect against infection by several viruses, bacteria, fungi, and parasites. Pinostrobin reduces the expression of proprotein convertase subtilisin/kexin type 9 (PCSK9), which is a promising target of lipid-lowering drugs. It also reduces high uric acid levels while not affecting the normal uric acid levels. Furthermore, it has protective effects on the liver, kidney, bone, skin, reproductive system, stomach and nerves. Due to its multifunctional effects and safety, pinostrobin has advantages for development as a novel drug for clinical application. Based on this, this current article summarized the research progress on the pharmacological effects and mechanisms of pinostrobin, to provide a reference for further development.

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Section: Anticancer Effectsmentioning

confidence: 99%

Research Progress on the Pharmacological Effects and Molecular Mechanisms of Pinostrobin

Wang,

Zhao,

Chen

et al. 2023

Natural Product Communications

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“…Alzheimer disease (AD) is a neurological disorder in which there is impairment in cognition and language comprehension [1]. Worldwide prevalence of Alzheimer diseases is nearly about 24 million and the risk of incidence get double after 65 years of age [2]. It is an estimate that 50 million peoples are suffering from this disease globally and it will rise to 150 million by the year 2050 [3].…”

Section: Introductionmentioning

confidence: 99%

“…The most common symptoms of Alzheimer's disease is impairment of short term memory and later on problem solving capacity, language integration behavior change occur . [2].…”

Section: Introductionmentioning

confidence: 99%

Magnesium and Memory: Unraveling the Physiological Tapestry of Alzheimer's Disease

Uddin,

Waheed,

Chohan

et al. 2024

JSRR

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Background: Alzheimer disease is the leading cause of Dementia throughout the world. There are multiple researches are undergoing globally to understand the etiology of this disabling disease. Magnesium is another suspicious factor that might produce this disease. Objectives: The study was aimed to evaluate possible association between serum magnesium and Alzheimer disease. Methodology: This case control study was conducted in the emergency Department in collaboration of Medical OPD of Liquate University Hospital Hyderabad from January 2023 to December 2023. 300 participants were divided into control, 200 participants and 100 in the test group. Serum Magnesium was evaluated into both control and test group. Graph Pad Prism 9 was used to detect P value. Significance of variable was considered below 0.05. Results: Those who were suffering from Alzheimer disease shows more Hypomagnesaemia (p-value= 0.001) than normal patients. The low serum Magnesium level was found 3.1 times greater (Odds ratio= 5.5, likelihood ratio= 1.9) in Alzheimer patients Conclusion: there is a specific association between Hypomagnesaemia and Alzheimer disease.

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Effect of Chinese herbal medicine on lung disease: an updated review

Cited by 2 publications

References 0 publications

Research Progress on the Pharmacological Effects and Molecular Mechanisms of Pinostrobin

Research Progress on the Pharmacological Effects and Molecular Mechanisms of Pinostrobin

Magnesium and Memory: Unraveling the Physiological Tapestry of Alzheimer's Disease

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