Effect of chlorhexidine chip in the treatment of chronic periodontitis

Abstract

Aims:The evaluation of clinical and specific microbiological changes associated with chlorhexidine chip in the chronic periodontitis patients.Materials and Methods:A total of 30 chronic periodontitis patients (aged 20-65 years) having pocket depth of ≥5 mm in molar teeth were selected and randomly divided into following treatment groups: Group 1 - Scaling and root planning (SRP), Group 2 - SRP along with chlorhexidine chip and Group 3 - Only chlorhexidine chip. The clinical and microbial parameters were recorded at baseline and 1 and 3 months post-treatment as above. Benzoyl-DL-arginine-naphthylamide (BANA) chair side test was used for estimation of specific microbiota.Results:Gingival index, probing pocket depth and clinical attachment level scores in selected teeth within the groups at different time intervals was significantly (P < 0.001) different. Although, the comparison between groups for specific microbiota in selected sites at different intervals was not statistically significant at baseline and 1 month, it reached statistical significance at 3rd month post-treatment. Although significant reductions in percentage of BANA positive sites were observed in all three groups, the Group 2 had significantly greater percentage of BANA negative sites.Conclusion:Local drug delivery using chlorhexidine chip enhances the benefit of SRP in the treatment of chronic periodontitis.

Chlorhexidine in Dentistry: Pharmacology, Uses, and Adverse Effects

“…Periodontal disease is a complex multifactorial inflammatory oral disease categorised by destruction of periodontal tissues and loss of the connective tissue attachment. 37 , 38 , 39 Once the diagnosis is made, it must be categorised by the process of staging and grading; this is a significant change from the previous classification system. 40 Gingivitis and periodontitis are a continuum of the same inflammatory disease, and although not all patients with gingivitis will progress to periodontitis, the management of gingivitis is the primary prevention strategy for periodontitis.…”

Evaluation of the effect of hydrogen peroxide as a mouthwash in comparison with chlorhexidine in chronic periodontitis patients: A clinical study

“…The greatest success has been with CHX, which is now considered the gold standard, against which other potential antiplaque agents are measured. [ 28 ] However, the local side effects of CHX, particularly extrinsic staining and taste aberrations, may limit its long-term use in oral hygiene products. [ 29 ]…”

Efficacy of Different Concentrations of Chlorhexidine Mouthwash on Plaque Accumulation and Periodontal Parameters

“…This study suggested that local drug delivery via CHX chip improves the advantage of scaling and root planing in the treatment of chronic periodontitis. 24 Furthermore, clinical evaluation of periodontal tissue after treatment of 40 patients by drugs containing CHX indicated that CHX should be most frequently utilized as a drug adjunct for the treatment of classic periodontitis, particularly in forms that can be administrated directly into periodontal pockets. 20…”