Effect of chloroquine prophylaxis during pregnancy on maternal haematocrit

Cot, Michel; Hesran, J.-Y. Le; Miailhes, Patrick; Roisin, A.; Fiévet, Nadine; Barro, D.; Etya’ale, Daniel; Deloron, Philippe; Coriat, Pierre; Breart, Gérard

doi:10.1080/00034983.1998.11813259

Cited by 15 publications

(18 citation statements)

References 20 publications

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“…13,[15][16][17]20, We conducted a literature search using MEDLINE, crossreferencing the following terms: 1) malaria or falciparum malaria, 2) pregnancy, pregnancy complications, or pregnancy complications infectious, 3) HIV or HIV-1, and 4) anemia. For the designated years of 1985-2000, this review yielded 789 articles for categories 1ϩ2 (malaria and pregnancy), 55 articles for categories 1ϩ2ϩ3, 98 articles for categories 1ϩ2ϩ4, and 15 articles for categories 1ϩ2ϩ3ϩ4.…”

Section: Data Reviewmentioning

confidence: 99%

“…[8][9][10][11][12][13][14][15][16][17][18][19][20] Because of high rates of parasitemia in pregnancy, particularly in many settings in sub-Saharan Africa, the World Health Organization has recommended presumptive malarial treatment followed by additional prevention measures during pregnancy. 11 Plasmodium falciparum infection in pregnancy leads to parasite sequestration in the maternal placental vascular space, with consequent maternal anemia 7,12,13 and infant low birth weight (LBW) [8][9][10][14][15][16][17] due to both prematurity 15,17 and intrauterine growth retardation (IUGR); 8,14,15,17 LBW is known to be the most important risk factor for infant mortality. 18,19 Anemia, undernutrition, and human immunodeficiency virus (HIV) infection are also common events in malarious areas and contribute to LBW.…”

Section: Introductionmentioning

confidence: 99%

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The burden of malaria in pregnancy in malaria-endemic areas

Steketee¹,

Nahlen²,

Parise³

et al. 2001

The American Journal of Tropical Medicine and Hygiene

881

721

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Abstract. Pregnant women in malarious areas may experience a variety of adverse consequences from malaria infection including maternal anemia, placental accumulation of parasites, low birth weight (LBW) from prematurity and intrauterine growth retardation (IUGR), fetal parasite exposure and congenital infection, and infant mortality (IM) linked to preterm-LBW and IUGR-LBW. We reviewed studies between 1985 and 2000 and summarized the malaria population attributable risk (PAR) that accounts for both the prevalence of the risk factors in the population and the magnitude of the associated risk for anemia, LBW, and IM. Consequences from anemia and human immunodeficiency virus infection in these studies were also considered. Population attributable risks were substantial: malaria was associated with anemia (PAR range ϭ 3-

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Section: Data Reviewmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The burden of malaria in pregnancy in malaria-endemic areas

Steketee¹,

Nahlen²,

Parise³

et al. 2001

The American Journal of Tropical Medicine and Hygiene

881

721

View full text Add to dashboard Cite

show abstract

“…Table 2 for the data sources for anemia and malaria parasite ratio. Five studies measuring hemoglobin in all parities could not be matched with a malaria parasite ratio: Banfora (Burkina Faso), 5 Lagos (Nigeria), 48 Benin City (Nigeria), 40 Monrovia (Liberia), 29 and Ubangi (Zaire). 74 of stable malaria transmission.…”

mentioning

confidence: 99%

“…The numbers refer to the data source for the mean hemoglobin value: 1 ϭ Addis Ababa (Ethiopia); 2 ϭ Nouakchott (Mauritania) ; 3 ϭ Harare (Zimbabwe); 4 ϭ Kaduna (Nigeria); 5 ϭ Dar-es-Salaam (Tanzania); 6 ϭ Makindye (Kampala); 7 ϭ Abidjan (Ivory Coast); 8 ϭ Kilifi (Kenya); 9 ϭ Zanzibar (Tanzania); 10 ϭ Accra (Ghana); 11 ϭ Zaria (Nigeria); 12 ϭ Kimpese (Zaire); 13 ϭ Chikwawa (Malawi); 14 ϭ Asembo, Siaya, and Bondo (Kenya), 15 ϭ Muheza (Tanzania). Five study sites measuring hemoglobin in all parities could not be matched with a malaria parasite ratio: Benin City (Nigeria), 40 Nchelenge (Zambia), 77 Nangina (Kenya), 26 Banfora (Burkina Faso), 5 and Ebolowa (Cameroon). 5 …”

mentioning

confidence: 99%

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The epidemiology and burden of Plasmodium falciparum-related anemia among pregnant women in sub-Saharan Africa

Guyatt¹,

Snow²

2001

The American Journal of Tropical Medicine and Hygiene

226

170

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Abstract. The paucity of precise information on the burden of malaria among pregnant women has hampered effective lobbying for the inclusion of preventative strategies against malaria in Safe Motherhood Initiatives. This article reviews the evidence on the coincidental risks of malaria and anemia in Africa and attempts to estimate the probable burden of malaria-related severe anemia in this susceptible group. Twenty-six studies on hemoglobin levels in all-parity pregnant women throughout this region could be matched with a malaria parasite ratio in children Ͻ 15 yr old (a measure of the intensity of transmission). In areas with no malaria, the mean hemoglobin levels were markedly higher than those found in areas with stable malaria transmission, though changes with increasing intensity of transmission were unclear. Eighteen studies from areas with stable malaria transmission in sub-Saharan Africa suggested that the median prevalence of severe anemia in all-parity pregnant women is approximately 8.2%. Assuming that 26% of these cases are due to malaria, it is suggested that as many as 400,000 pregnant women may have developed severe anemia as a result of infection with malaria in sub-Saharan Africa in 1995.

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Diagnosis of Plasmoduim falciparum malaria in pregnancy in sub-Saharan Africa: the challenges and public health implications

Uneke

2007

Parasitol Res

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Plasmodium falciparum malaria in pregnancy is a major public health problem in sub-Saharan Africa and represents enormous diagnostic challenge. The objective of this report was to review scientific data from studies conducted in sub-Saharan Africa on the diagnosis of malaria in pregnancy within the last two decades (1987 to 2007), to highlight the challenges and the public health implications. Using the Medline Entrez-Pubmed search, relevant publications were identified for the review via combinations of key words such as Malaria, Pregnancy, and Sub-Saharan Africa, which yielded 777 entries as of September 2007. The results from the various studies were discordant, due to differences in the techniques of sample collection and analysis, based on the differences in the definition of clinical, peripheral, and placental malaria. Definitions were based on the presence of malaria parasite and/or pigments in blood smear from peripheral/placental blood, on histological placental findings, on the use of rapid diagnostic tests (RDTs) and polymerase chain reaction (PCR). Nonspecific clinical presentation of malaria, lack of efficient diagnostic facilities and trained personnel, and absence of regulatory standards for diagnostic tests, are some of the major diagnostic challenges. Increased allocation of resources to development and application of accurate diagnostics will improve malaria diagnosis in pregnancy.

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Effect of chloroquine prophylaxis during pregnancy on maternal haematocrit

Cited by 15 publications

References 20 publications

The burden of malaria in pregnancy in malaria-endemic areas

The burden of malaria in pregnancy in malaria-endemic areas

The epidemiology and burden of Plasmodium falciparum-related anemia among pregnant women in sub-Saharan Africa

Diagnosis of Plasmoduim falciparum malaria in pregnancy in sub-Saharan Africa: the challenges and public health implications

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