Effect of chronic lithium chloride on membrane adenosine triphosphatases in certain postural muscles of rats

Adipudi, Vijayalakshimi; Reddy, V. Krishna

doi:10.1016/0014-2999(94)90150-3

Cited by 18 publications

(4 citation statements)

References 43 publications

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“…In animals, lack of magnesium in their diet leads to increased free radical production [26], while magnesium supplementation eliminates free radical production induced by ischemia reperfusion [23] and alcohol drinking [27]. Lithium can increase the free radical scavenging capability in animals [25] and thus help to increase the resilience of a cell against destructive free radical attack [28]. …”

Section: Discussionmentioning

confidence: 99%

Deep ocean mineral water accelerates recovery from physical fatigue

Hou¹,

Tsai²,

Jean

et al. 2013

Journal of the International Society of Sports Nutrition

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BackgroundDeep oceans have been suggested as a possible site where the origin of life occurred. Along with this theoretical lineage, experiments using components from deep ocean water to recreate life is underway. Here, we propose that if terrestrial organisms indeed evolved from deep oceans, supply of deep ocean mineral water (DOM) to humans, as a land creature, may replenish loss of molecular complexity associated with evolutionary sea-to-land migration.MethodsWe conducted a randomized, double-blind, placebo-controlled crossover human study to evaluate the effect of DOM, taken from a depth of 662 meters off the coast of Hualien, Taiwan, on time of recovery from a fatiguing exercise conducted at 30°C.ResultsThe fatiguing exercise protocol caused a protracted reduction in aerobic power (reduced VO2max) for 48 h. However, DOM supplementation resulted in complete recovery of aerobic power within 4 h (P < 0.05). Muscle power was also elevated above placebo levels within 24 h of recovery (P < 0.05). Increased circulating creatine kinase (CK) and myoglobin, indicatives of exercise-induced muscle damage, were completely eliminated by DOM (P < 0.05) in parallel with attenuated oxidative damage (P < 0.05).ConclusionOur results provide compelling evidence that DOM contains soluble elements, which can increase human recovery following an exhaustive physical challenge.

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Section: Discussionmentioning

confidence: 99%

Deep ocean mineral water accelerates recovery from physical fatigue

Hou¹,

Tsai²,

Jean

et al. 2013

Journal of the International Society of Sports Nutrition

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“…Coenzyme Q is the important electronic delivery vector of mitochondrial respiratory chain redox and contributes to mitochondrial ATP synthesis, as well as non-enzymatic antioxidants (35). Lithium can increase the capability for scavenging free radical in animals, and increases the resilience of a cell against destructive free radical attack (18,36). In addition, trace elements such as copper and zinc are highly correlated to antioxidants (37).…”

Section: Groupmentioning

confidence: 99%

Deep sea water improves exercise and inhibits oxidative stress in a physical fatigue mouse model

Fan¹,

Tan²,

Yue³

et al. 2016

Biomedical Reports

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Abstract. Physical fatigue is extremely common and occurs daily, and is considered to be associated with oxidative stress. The diverse functions of deep sea water (DSW) have recently gained increasing attention. Previous studies have emphasized the anti-fatigue effect of DSW, but the intrinsic mechanism behind the effect remains to be elucidated. In the imprinting control region (ICR) mice model, DSW delayed the exhaustive swimming time. In addition, DSW decreased the area under the blood lactate (BLA) curve, which was associated with the area under the BLA curve of pre-swimming, post-swimming and post-rest. Furthermore, DSW reduced the basal levels of malondialdehyde and the post-swimming concentration of blood urea nitrogen, lactate dehydrogenase and creatine kinase after swimming, along with an increase in the normal level of antioxidant enzyme activity such as superoxide dismutase and glutathione peroxidase. However, no significant effect on body weight, hepatic glycogen and muscle glycogen was observed between any group. In conclusion, DSW can improve the athletic ability and alleviate physical fatigue of ICR mice. This effect is achieved by enhancing the antioxidant capacity.

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“…Using electrophysiological recordings from hippocampal slices, previous studies have shown that cannabinoid receptor activation inhibits LTP in the hippocampus [7]–[11]. We have shown that acute administration of the CB1/2 receptor agonist WIN55,212-2 (WIN; 0.5 mg/kg) impairs the induction of LTP in the schaffer collateral-CA1 projection of anesthetized rats [12].…”

Section: Introductionmentioning

confidence: 99%

Short- and Long-Term Cognitive Effects of Chronic Cannabinoids Administration in Late-Adolescence Rats

2012

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The use of cannabis can impair cognitive function, especially short-term memory. A controversial question is whether long-term cannabis use during the late-adolescence period can cause irreversible deficits in higher brain function that persist after drug use stops. In order to examine the short- and long-term effects of chronic exposure to cannabinoids, rats were administered chronic i.p. treatment with the CB1/CB2 receptor agonist WIN55,212-2 (WIN; 1.2 mg/kg) for two weeks during the late adolescence period (post-natal days 45–60) and tested for behavioral and electrophysiological measures of cognitive performance 24 hrs, 10 and 30 days after the last drug injection. The impairing effects of chronic WIN on short-term memory in the water maze and the object recognition tasks as well as long-term potentiation (LTP) in the ventral subiculum (vSub)-nucleus accumbens (NAc) pathway were temporary as they lasted only 24 h or 10 d after withdrawal. However, chronic WIN significantly impaired hippocampal dependent short-term memory measured in the object location task 24 hrs, 10, 30, and 75 days after the last drug injection. Our findings suggest that some forms of hippocampal-dependent short-term memory are sensitive to chronic cannabinoid administration but other cognitive impairments are temporary and probably result from a residue of cannabinoids in the brain or acute withdrawal effects from cannabinoids. Understanding the effects of cannabinoids on cognitive function may provide us with tools to overcome these impairments and for cannabinoids to be more favorably considered for clinical use.

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Effect of chronic lithium chloride on membrane adenosine triphosphatases in certain postural muscles of rats

Cited by 18 publications

References 43 publications

Deep ocean mineral water accelerates recovery from physical fatigue

Deep ocean mineral water accelerates recovery from physical fatigue

Deep sea water improves exercise and inhibits oxidative stress in a physical fatigue mouse model

Short- and Long-Term Cognitive Effects of Chronic Cannabinoids Administration in Late-Adolescence Rats

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