Effect of co-administration of atelocollagen and hyaluronic acid on rotator cuff healing

Jeong, Jeung Yeol; Khil, Eun Kyung; Kim, Tae Soung; Kim, Young Woo

doi:10.5397/cise.2021.00234

Cited by 17 publications

(10 citation statements)

References 38 publications

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“…2,14 Most studies reported improved clinical outcomes, especially in the VAS pain score. 2,[12][13][14][15] In the present study, intraoperative addition of atelocollagen did not improve outcome scores. However, there was slighter greater ROM.…”

Section: Discussioncontrasting

confidence: 60%

“…For gel-type atelocollagen delivery, the injection is performed directly to the tear site using ultrasound in the outpatient clinics 2,15 or intraoperatively after rotator cuff repair. 12,14 Table 3 summarizes the findings of 2 level 1 randomized controlled trials that reported on clinical applications of atelocollagen. 12,15 Using gel-type atelocollagen injection, Jeong et al 12 observed an additional effect after coinjection of atelocollagen and hyaluronic acid.…”

Section: Discussionmentioning

confidence: 99%

“…12,14 Table 3 summarizes the findings of 2 level 1 randomized controlled trials that reported on clinical applications of atelocollagen. 12,15 Using gel-type atelocollagen injection, Jeong et al 12 observed an additional effect after coinjection of atelocollagen and hyaluronic acid. These authors found that coadministration of atelocollagen and hyaluronic acid did not differ significantly in terms of the clinical findings; however, it led to decreased retear rates (P \ .05) and improved rotator cuff healing and increased the integrity of the rotator cuff repair site.…”

Section: Discussionmentioning

confidence: 99%

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Effects of Arthroscopic Atelocollagen Insertion in High-Grade Partial Articular Supraspinatus Tendon Avulsion Lesions: A Retrospective Cohort Study With Propensity Score Matching

Ji,

Choi,

You

et al. 2023

Orthopaedic Journal of Sports Medicine

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Background: This study sought to evaluate the effect of atelocollagen insertion into the bone–tendon interface of the repaired tendon after arthroscopic rotator cuff repair for high-grade partial articular supraspinatus tendon avulsion (PASTA) lesions. Purpose: To compare clinical and radiological outcomes of atelocollagen-inserted rotator cuff repair and atelocollagen-noninserted rotator cuff repair in the high-grade PASTA lesions. Study Design: Cohort study; Level of evidence, 3. Methods: The data from 301 consecutive patients who underwent arthroscopic rotator cuff repair of PASTA lesions between January 2017 and June 2020 were retrospectively reviewed. Patients with minimum 2-year follow-up data were included and divided into 2 groups: those treated with transtendon suture-bridge repair without additional augmentation (group 1) and those with atelocollagen-inserted transtendon suture-bridge repair (group 2). Patients in group 2 were matched 1:1 to patients in group 1 using propensity score matching (n = 68 per group); and pain visual analog scale, American Shoulder and Elbow Surgeons, University of California, Los Angeles, Korean Shoulder Scoring System, Simple Shoulder Test, and range of motion scores were compared between these groups. Also, repaired tendon integrity and thickness were compared immediately, 6 months, and 1 year after surgery on magnetic resonance imaging (MRI) using the vertical distance from the midpoint footprint of the greater tuberosity. Results: In most comparisons, there were no significant differences in outcome measures and range of motion between groups. However, less residual discomfort at the final follow-up was also documented in group 2 ( P = .043). Also, the difference in forward flexion was 3.7° at 1 year and 5.4° at final follow-up, and the difference in abduction was 2.2° at final follow-up, which were all significantly greater in the experimental group. Group 2 showed significant greater tendon thickness of the repaired tendon immediately, 6 months, and 1 year after surgery on MRI ( P≤ .001). Conclusion: Addition of atelocollagen did not improve outcome scores. However, there was slightly greater flexion and abduction at final follow-up. Also, there was less residual discomfort at final follow-up.

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Section: Discussioncontrasting

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Effects of Arthroscopic Atelocollagen Insertion in High-Grade Partial Articular Supraspinatus Tendon Avulsion Lesions: A Retrospective Cohort Study With Propensity Score Matching

Ji,

Choi,

You

et al. 2023

Orthopaedic Journal of Sports Medicine

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“…Rotator cuff tears are a common clinical problem with multifactorial etiology including degenerative changes and trauma. A commonly accepted and widely used treatment approach for rotator cuff tears involves arthroscopic repair [1][2][3] . Although most patients experience satisfactory clinical outcomes after arthroscopic rotator cuff repair (ARCR), potential complications have also been reported from a number of studies [4][5][6][7] .…”

mentioning

confidence: 99%

Incidence and risk factors for early postoperative stiffness after arthroscopic rotator cuff repair in patients without preoperative stiffness

Cho

Bae

Kim

2022

Sci Rep

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The purpose of this study was to investigate the incidence and risk factors of early postoperative stiffness in patients without preoperative stiffness undergoing isolated arthroscopic rotator cuff repair (ARCR). Two hundred seventy-four patients who underwent primary ARCR were included. At 3 months after surgery, criteria for shoulder stiffness was set as follows: (1) passive forward flexion < 120˚, or (2) external rotation at side < 30˚. Patients with preoperative stiffness or who underwent additional procedures were excluded. Patients-related, radiological (muscle atrophy and fatty infiltration), and intraoperative (tear size, repair techniques, number of anchors used, and synovitis scores) risk factors were analyzed. Univariate and multivariate analyses were used to identify risk factors for postoperative stiffness. Thirty-nine of 274 patients (14.2%) who underwent ARCR developed postoperative stiffness. Univariate analyses revealed that early postoperative stiffness was significantly associated with diabetes mellitus (p = 0.030). However, radiological and intraoperative factors did not affect postoperative shoulder stiffness (all p > 0.05). Multivariate analyses revealed early postoperative stiffness was significantly associated with diabetes mellitus and timing of rehabilitation (p = 0.024, p = 0.033, respectively). The overall incidence of early postoperative stiffness following isolated ARCR in patients without preoperative stiffness was 14.2%. Diabetes mellitus and timing of rehabilitation were independent risk factors for early postoperative stiffness following ARCR.

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“…향상을 통해서 부분파열 및 회전 근개 건병증의 치료에 PRP 주사, 증식치료(prolotherapy) 나 polydeoxyribonucleotide 주사, atelocollagen 주사[25] 등 재생치료가 시도되고 있다. 또한 혈소판에 풍부한 성장인 자를 손상이 있는 부분에 투여하여 생체의 치유능력을 향상 을 통해 조직의 치유를 기대해 볼 수 있으며, 최근 연구에 따 르면 PRP가 건침에 비하여 회전근개의 치유를 위한 성장인 자를 모이게 하며[12], 스테로이드 주사만큼 통증 조절에 효 과적이라는 보고가 있다[26].…”

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Nonoperative treatment of shoulder pain

Kim¹,

Chung²

2022

J Korean Med Assoc

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Background: The shoulder joint has a wide range of motion and is extensively used. Damage in its components may cause functional deficits and pain. In particular, shoulder joint pain is associated with discomfort due to the involvement of the joint’s movement in basic tasks of daily life, such as washing one’s hair, dressing, and eating.Current Concepts: Diseases that cause shoulder joint pain include shoulder impingement syndrome, rotator cuff tear and tendinopathy, lesion of superior labrum anterior to posterior, biceps tendinitis, adhesive capsulitis, calcific tendinitis, and shoulder instability. Nonoperative treatment of shoulder joint pain includes: (1) reducing pain and preventing structural damage through rest, lifestyle modification, and physical therapy; (2) reducing pain through drug and injection treatment; (3) strengthening the rotator cuff muscles, around the scapula; and (4) performing scapular stabilization treatment through muscle strengthening. These treatments maintain the biomechanics of the shoulder joint, prevent disease progression, and enable pain-free daily life and exercise through symptom relief.Discussion and Conclusion: It is necessary to have an accurate understanding of the structures that cause shoulder joint pain. Understanding the cause of the pain can prevent the disease from progressing. Nonoperative management for shoulder pain consists of preventing a decrease in the range of motion of the shoulder joint with reduction of pain relief, preventing inflammation through drug treatment, injection treatment, lifestyle modifications, and improving muscle strength of the muscles around the rotator cuff and periscapular muscle joint through rehabilitation exercise. Nonoperative treatment modalities are valuable and cost-effective management options for shoulder pain.

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Effect of co-administration of atelocollagen and hyaluronic acid on rotator cuff healing

Cited by 17 publications

References 38 publications

Effects of Arthroscopic Atelocollagen Insertion in High-Grade Partial Articular Supraspinatus Tendon Avulsion Lesions: A Retrospective Cohort Study With Propensity Score Matching

Effects of Arthroscopic Atelocollagen Insertion in High-Grade Partial Articular Supraspinatus Tendon Avulsion Lesions: A Retrospective Cohort Study With Propensity Score Matching

Incidence and risk factors for early postoperative stiffness after arthroscopic rotator cuff repair in patients without preoperative stiffness

Nonoperative treatment of shoulder pain

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