Effect of Coconut Oil Administration on Some Hemostatic Changes Associated with Obesity in Rats

Mohamed, Fatma; Bahgat, Nehal M.; Hamed, Gehane M.; Eisa, Rania S.A.

doi:10.21608/ejhm.2009.17474

Cited by 4 publications

(1 citation statement)

References 22 publications

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“…Hipercalory pellet produced by PT Indofeed with nutritional value: The hypercaloric solution was made based on a combination of research from Al-Attar (2010), Maryani et.al. (2016), Mohamed & Bahgat (2009), Ruslin et.al. (2019, Senaphan et al (2015) so it was made with the composition: quail egg yolk (40%), goat fat (25%), fructose (20%), pure salt (4%), coconut oil (5%) and Na-CMC solution (ad 100 %).…”

Section: Methodsmentioning

confidence: 98%

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Iqbal¹,

Saputri²,

Mun’im³

et al. 2023

J. Sci. n.a

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Section: Methodsmentioning

confidence: 98%

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Iqbal¹,

Saputri²,

Mun’im³

et al. 2023

J. Sci. n.a

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Effects of different diets used in diet-induced obesity models on insulin resistance and vascular dysfunction in C57BL/6 mice

Lang

Hasselwander

et al. 2019

Sci Rep

109

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The aim of the present study was to compare different diets used to induce obesity in a head-to-head manner with a focus on insulin resistance and vascular dysfunction. Male C57BL/6J mice were put on standard chow diet (SCD), normal-fat diet (NFD), cafeteria diet (CAF) or high-fat diet (HFD) for 12 weeks starting at the age of 6 weeks. Both CAF and HFD led to obesity (weight gain of 179% and 194%, respectively), glucose intolerance and insulin resistance to a comparable extent. In aortas containing perivascular adipose tissue (PVAT), acetylcholine-induced vasodilation was best in the NFD group and worst in the CAF group. Reduced phosphorylation of endothelial nitric oxide synthase at serine 1177 was observed in both CAF and HFD groups. Plasma coagulation activity was highest in the HFD group and lowest in the SCD group. Even the NFD group had significantly higher coagulation activity than the SCD group. In conclusions, CAF and HFD are both reliable mouse diets in inducing visceral obesity, glucose intolerance and insulin resistance. CAF is more effective than HFD in causing PVAT dysfunction and vascular dysfunction, whereas hypercoagulability was mostly evident in the HFD group. Coagulation activity was higher in NFD than NCD group.

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تاثیر ثمار جوز الهند على بعض التغیرات البیولوجیة فی الفئران المصابة بالسمنة

إمام¹

2019

مجلة البحوث فی مجالات التربیة النوعیة

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T he aim targets of this works is study the effect of coconut kernel powder with different ratio 5,10 and 15% on chemical, biological changes of rats induced obesity. Chemical composition, phenols, flavonoids, DPPH radical assay and fatty acids of coconut powder were studied. In addition, biological parameters were studied. Results showed that it could be concluded that coconut kernel powder is considered as a good source of oil, crude fiber, ash content, protein carbohydrates, total calories and has an antioxidant properties. Also it is a rich source of medium-chain triglyceride, mainly lauric acid, with approximately have the amount of fatty acids. Total saturated fatty acids represent 94.59%. Biological evaluation revealed that obesity rats fed on diet supplemented by coconut powder showed significant decrease (P ≤ 0.05) of body weight, total lipids, cholesterol, triglyceride, LDLC and VLDLC. In addition, diet containing coconut powder significant decreased (P≤ 0.05) in liver enzymes (AST, ALT and LAP) and kidney functions (urea, uric acid and creatinine) of obesity rats. Moreover, increased both serum protein and albumin and lowering blood glucose. Were observed.

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Effect of Coconut Oil Administration on Some Hemostatic Changes Associated with Obesity in Rats

Cited by 4 publications

References 22 publications

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Metabolic Syndrome Induced by Hipercalory Diet in Wistar Rats: impact on diabetic risk, dyslipidemia and hypertension complication

Effects of different diets used in diet-induced obesity models on insulin resistance and vascular dysfunction in C57BL/6 mice

تاثیر ثمار جوز الهند على بعض التغیرات البیولوجیة فی الفئران المصابة بالسمنة

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