“…Alternatively, most psychotherapeutic treatments (including both cognitive behavioral therapy and mindfulness treatments) are typically associated with positive long-term side effects, including improved physical health (e.g., Murphy, Mermelstein, Edwards, & Gidycz, 2012) and ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 5 overall quality of life (e.g., Hofmann, Wu, & Boettcher, 2014). As such, when considering the importance of effect sizes, researchers and practitioners should balance the helpful effects of medications with the cost of their side effects, whereas this process is generally not necessary for psychotherapies, where secondary effects are more likely to be beneficial e.g., cognitive therapies targeting sexual dysfunction also lessening the frequently co-morbid mood disorder.…”