Effect of combined use of home blood pressure monitoring and nifedipine on blood pressure compliance and quality of life of patients with essential hypertension

Abstract

Purpose: To investigate the effect of combination of home blood pressure monitoring (HBPM) and nifedipine on blood pressure compliance and quality of life in patients with essential hypertension.
 Methods: One hundred and twenty essential hypertension patients admitted to Jiaozuo Coal Industry (Group) Co. Ltd Central Hospital from February 2020 to February 2021 were retrospectively studied. They were equally divided into study group (SG) and control group (COG) according to the order of admission. All patients were treated with nifedipine. Blood pressure was regularly measured in COG patients in the consulting room, while for SG patients, blood pressure was measured at home. Treatment compliance, blood pressure-related indices and quality of life of the two groups were determined.
 Results: Treatment compliance values of patients in SG at 6 weeks (T2) and 12 weeks (T3) were significantly better than the corresponding values for patients in COG (p < 0.05). The related indices of blood pressure at T2 and T3 were significantly better in SG than in COG (p < 0.05), with higher blood pressure compliance at T2 and T3 in SG (60 and 70 %, respectively) than in COG (p < 0.05). The quality-of-life scores at T3 in SG were significantly higher than those in COG (p < 0.05).
 Conclusion: The combined use of HBPM and nifedipine improves treatment compliance, enhances the levels of related indices of blood pressure, increases blood pressure compliance, and quality of life of patients with essential hypertension. Therefore, the combined therapy merits further investigation on a larger scale.

Comparative efficacy and safety of ginkgo-based Chinese patent medicines in patients with hypertension: A systematic review and network meta-analysis of randomized clinical trials

“…A total of 46 RCTs involving 8 ginkgo-based proprietary CPMs and 5183 participants were included in this study, including 21 items of ginkgo biloba tablet (GBT), [22–42] 3 items of GB capsule (GBC), [43–45] 6 items of ginkgo biloba drop (GBD), [46–51] 3 items of ginkgo biloba ketone ester drop (GBKED), [18,52,53] 2 items of Fufangyinxing capsule (FFYX), [54,55] 2 items of fufangyinxingtongmai oral liquid (FFYXTM), [56,57] 2 items of Yinxingmihuan oral liquid (YXMH), [58,59] and 7 items of Yindanxinanotong softgel capsule (YDXNT). [60–66] The basic characteristics of the included literature such as authors, time of publication, subject information (mean age, gender), interventions, duration of treatment, duration of follow-up, and outcome indicators are shown in Table 1.…”

“…Forty-six studies reported comparable baseline information between groups. Forty-four studies [18,22–41,43–57,59–66] did not mention blinding, 1 study [58] utilized double blinding, and 1 study [42] was single blinded. Regarding the outcome section, 45 studies [22–28,30–50] used tables combined with text to record the outcome indicators of the researchers, and 1 study [29] used textual descriptions, and none of them had missing outcome data.…”

“…Forty-four studies [18,22–41,43–57,59–66] did not mention blinding, 1 study [58] utilized double blinding, and 1 study [42] was single blinded. Regarding the outcome section, 45 studies [22–28,30–50] used tables combined with text to record the outcome indicators of the researchers, and 1 study [29] used textual descriptions, and none of them had missing outcome data. Forty-six studies [18,22–66] described in detail the methods of measuring the outcome indicators, and there were no multiple methods of outcome measurements and no multiple ways of analyzing them.…”

“…We assessed the risk of bias in 46 studies [18, using ROB 2.0. 1 study [53] was grouped according to the order of visit, 13 studies [27,28,35,36,40,47,50,[53][54][55][56]59,60] used the randomized table of numbers method, 3 studies [31,32,45] used the randomization by lot method, 1 study [49] used a random Total effective rate TC TG Tang Xinmei 2009 [24] 50/30 Han Xiangrui 2014 [37] 30/30 Kong Chunhui 2016 [43] 75/75 Fang Runbo 2019 [49] 100/100 Zheng Xuejing 2020 [58] 34/34 dice, 1 study [46] used 2-color random draws, and 27 studies [18,[22][23][24][25][26]29,30,33,34,[37][38][39]41,43,44,47,51,52,61,62,[64][65]…”

“…Forty-six studies reported comparable baseline information between groups. Forty-four studies [18,[22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][59][60][61][62][63][64][65][66] did not mention blinding, 1 study [58] utilized double blinding, and 1 study [42] was single blinded. Regarding the outcome section, 45 studies [22][23][24][25]…”