Background
Colonoscopy is considered to be an important tool for early diagnosis of colorectal lesions, screening for colorectal cancer, and to perform treatment of early colorectal lesions. Adequate bowel preparation is a prerequisite for high-quality colonoscopy and is closely related to the diagnostic accuracy and therapeutic safety of colonoscopy.Taking PEGs with sports drinks to regulate flavors, etc. May improve patient compliance and quality of bowel preparation. The aim of this study was to compare patient adherence and efficacy of the bowel cleanser PEG alternating with iced tea drink with the mixture of PEG and iced tea drink.
Methods
This is a prospective randomised controlled study conducted in a tertiary care hospital in Jiaxing, Zhejiang Province, China. A total of 300 patients who underwent painless gastroenteroscopy at the endoscopy center from July 2023 to June 2024 were selected and randomly divided into three groups, A,B,C. Each group consisted of 100 patients, all of whom were given 3 L of Polyethylene Glycol Electrolyte Dispersions (PEG) regimen in divided doses, i.e., 1 L 10 ~ 12 h prior to the intestinal examination, and 4–6 h prior to the examination on the day of the examination Group A was given 3 L of PEG all in lukewarm water, Group B was given PEG 1.5 L of warm water + 1.5 L of iced tea drink mixture, Group C took PEG 1.5 L of warm water while alternating with 1.5 L of iced tea drink. The number of patient's bowel movements, nature of bowel movements, whether they vomited or not, whether they took all of them or not, evaluation of the taste of PEG purgative, and willingness to be re-examined were carried out in the three groups. The endoscopic medical staff objectively evaluated the clarity of bowel vision and bowel preparation scores and statistically analyzed them.
Results
In this study, there was no significant difference in defecation frequency and defecation characteristics among the three groups of patients (P > 0.05). However, in terms of whether the PEG solution was drunk, whether there was vomiting, and the taste of the bowel cleansing agent, group C performed significantly better than groups A and B (P < 0.01). Compared with Group A, Group B also performed better in these aspects. Group C also performed well in terms of Bowel Preparation Quality, Check willingness again, Clear view of intestines, and whether there were polyps, which was significantly higher than the other two groups (P < 0.05).
Conclusion
The overall evaluation of complex polyethylene glycol electrolyte powder taken alternately with iced tea beverage before colonoscopy was superior and clinical promotion is recommended.
Registration:
ChiCTR2300075025(2023-10-08).