Effect of concrete surface hydropobation treatment against chloride penetration have been studied by in-site exposure test. The results show that the silane impregnated layer can prevent the chlorides penetration into the concrete substrate effectively, reduce the apparent chloride ion diffusion coefficient and surface chloride concentration, and improve the service life of concrete structure; and the depth of concrete convection zone can reduce due to silane impregnated layer for concrete in the marine environment of wetting and drying area.