Effect of Contrast, Stimulus Density, and Viewing Distance on Multifocal Steady-State Visual Evoked Potentials (MSVs)

Abdullah, Siti Nadia Binti; Aldahlawi, Nada Hussein; Rosli, Yanti; Vaegan,; Boon, Mei Ying; Maddess, Ted

doi:10.1167/iovs.11-9325

Cited by 14 publications

(19 citation statements)

References 34 publications

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“…The M100 responses showed substantial modulations based on the contrast of the image (see Figure 2) and did not change based on image noise or cognitive task. In accordance with previous electrophysiological studies (Abdullah et al 2012;Gebodh, Vanegas, and Kelly 2017;Maddess, James, and Bowman 2005), high contrast stimuli elicited larger and faster M100 responses as compared to low contrast stimuli (p<.001).…”

Section: Meg Resultssupporting

confidence: 92%

“…The M100 responses showed substantial modulations based on the contrast of the image (see Figure 2) and did not change based on image noise or cognitive task. In accordance with previous electrophysiological studies (Abdullah et al 2012;Gebodh, Vanegas, and Similar FA correlations were found with the other M100 electrophysiological properties (amplitude: r=+0.29, p=0.04, robust r=+0.35, p=0.02; power: r=+0.34, p=0.02, robust r=+0.34, p=0.02; inter-trial coherence: r=+0.29, p=0.04, robust r=+0.29, p=0.04).…”

Section: Meg Resultssupporting

confidence: 91%

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Development of the visual white matter pathways mediates development of electrophysiological responses in visual cortex

Caffarra

Joo

Bloom³

et al. 2021

Preprint

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The latency of neural responses in the visual cortex changes systematically across the lifespan. Here we test the hypothesis that development of visual white matter pathways mediates maturational changes in conduction velocities of visual signals. Thirty-eight children participated in a cross-sectional study including diffusion MRI and MEG sessions. During the MEG acquisition, participants performed a lexical decision and a fixation task on words presented at varying levels of contrast and noise. For all stimuli and tasks, early evoked fields were observed around 100 ms after stimulus onset (M100), with slower and lower amplitude responses for low as compared to high contrast stimuli. The optic radiations and optic tracts were identified in each individual's brain based on diffusion MRI tractography. The diffusion properties of the optic radiations predicted M100 responses, especially for high contrast stimuli. Higher optic radiation fractional anisotropy (FA) values were associated with faster and larger M100 responses. Over this developmental window, the M100 responses to high contrast stimuli became faster with age and the optic radiation FA fully mediated this effect. These findings suggest that the maturation of the optic radiations over childhood accounts for individual variations observed in the developmental trajectory of visual cortex responses.

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Section: Meg Resultssupporting

confidence: 92%

“…The M100 responses showed substantial modulations based on the contrast of the image (see Figure 2) and did not change based on image noise or cognitive task. In accordance with previous electrophysiological studies (Abdullah et al 2012;Gebodh, Vanegas, and Similar FA correlations were found with the other M100 electrophysiological properties (amplitude: r=+0.29, p=0.04, robust r=+0.35, p=0.02; power: r=+0.34, p=0.02, robust r=+0.34, p=0.02; inter-trial coherence: r=+0.29, p=0.04, robust r=+0.29, p=0.04).…”

Section: Meg Resultssupporting

confidence: 91%

Development of the visual white matter pathways mediates development of electrophysiological responses in visual cortex

Caffarra

Joo

Bloom³

et al. 2021

Preprint

View full text Add to dashboard Cite

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“…However, in the midfrequency range, the recordings were sufficiently short for clinical application (e.g., 91.5 seconds at 12 Hz). This is close to the resolution presented earlier 5,31…”

Section: Discussionsupporting

confidence: 90%

“…So far, quadrant recordings with pattern-reversal stimulation were made with separate stimulation of each field quadrant 20–22. More recently, Maddess and colleagues23 demonstrated the value of the incommensurate frequency technique for grating stimulation on a monitor with several discrete reversal frequencies. In the present study, we show that LEDs can be used in arrays that can deliver pattern-reversal stimuli with very small temporal frequency differences.…”

Section: Discussionmentioning

confidence: 99%

Steady-State Visually Evoked Potentials Elicited by Multifrequency Pattern-Reversal Stimulation

Hohberger

Kremers

Horn

2019

Trans. Vis. Sci. Tech.

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Purpose It has been shown that multifrequency stimulation with multifocal electroretinography can reduce recording time without a loss in signal-to-noise ratio. Here, we studied the applicability of multifrequency stimulations for steady-state visually evoked potential (VEP) recordings. Methods Multifrequency VEPs were recorded monocularly from 10 healthy subjects using pattern-reversal stimuli. The reversal frequency varied between 5 and 30 Hz. Pattern-reversal checkerboard stimuli were generated using four square arrays, each containing 100 light-emitting diodes (LEDs), positioned in four quadrants. Each array had a temporal frequency that differed slightly from the nominal frequency. The long duration of the data acquisition ensured that the slightly different stimulus frequencies in the four LED arrays can be resolved and that the responses to the stimulus in each array can be distinguished (e.g., with a frequency resolution: 0.011 Hz at 12 Hz). The best response from the four recording electrode configuration, defined as the recording with the maximal signal-to-noise ratio, was used for further analysis. Algorithmic latencies were calculated from the ratio of phase data and frequencies in a range of 4 and 20 Hz. Results Quadrant-VEPs with simultaneous pattern-reversal stimulation yielded a significant dependency on temporal frequency and stimulus location. The frequency range leading to the maximal response amplitude was between 10 and 12 Hz. Response phases decreased approximately linearly, with increasing temporal frequency suggesting a mean algorithmic latency between 112 and 126 ms. Conclusions Multifrequency stimulation using LED arrays is an efficient method for recording pattern-reversal VEPs while all stimuli are presented at the same time. Translational Relevance Simultaneously recorded VEPs as performed by the multi-frequency method can be used for objective measurements of visual field defects.

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“…Since the use of multiple simultaneous inputs reduces the time needed for assessments (e.g., example of clinical visual field assessment) (Abdullah, Aldahlawi, Rosli, Boon, & Maddess, 2012), frequency-tagging EEG can be a very fast and efficient measure. Given the short recording time of the frequency-tagging paradigm and the robustness of the obtained results, the method could be used as a fast marker of social preference, which may ultimately be incorporated in the clinical diagnostic procedure.…”

Section: Discussionmentioning

confidence: 99%

Combined frequency-tagging EEG and eye tracking reveal reduced social bias in boys with autism spectrum disorder

Vettori

Dzhelyova

Donck

et al. 2020

Cortex

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Developmental accounts of autism spectrum disorder (ASD) state that infants and children with ASD are spontaneously less attracted by and less proficient in processing social stimuli such as faces. This is hypothesized to partly underlie social communication difficulties in ASD. While in some studies a reduced preference for social stimuli has been shown in individuals with ASD, effect sizes are moderate and vary across studies, stimuli, and designs. Eye tracking, often the methodology of choice to study social preference, conveys information about overt orienting processes but conceals covert attention, possibly resulting in an underestimation of the effects. In this study, we recorded eye tracking and electroencephalography (EEG) during fast periodic visual stimulation to address this issue. We tested 21 boys with ASD (8-12 years old) and 21 typically developing (TD) control boys, matched for age and IQ. Streams of variable images of faces were presented at 6 Hz alongside images of houses presented at 7.5 Hz or vice versa, while children were engaged in an orthogonal task. While frequency-tagged neural responses were larger in response to faces than simultaneously presented houses in both groups, this effect was much larger in TD boys than in boys with ASD. This group difference in saliency of social versus non-social processing is significant after 5 sec of stimulus presentation and holds throughout the entire trial. Although there was no interaction between group and stimulus category for simultaneously recorded eye-tracking data, eye tracking and EEG measures were strongly correlated. We conclude that frequency-tagging EEG, allowing monitoring of both overt and covert processes, provides a fast, objective and reliable measure of decreased preference for social information in ASD.

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Effect of Contrast, Stimulus Density, and Viewing Distance on Multifocal Steady-State Visual Evoked Potentials (MSVs)

Cited by 14 publications

References 34 publications

Development of the visual white matter pathways mediates development of electrophysiological responses in visual cortex

Development of the visual white matter pathways mediates development of electrophysiological responses in visual cortex

Steady-State Visually Evoked Potentials Elicited by Multifrequency Pattern-Reversal Stimulation

Combined frequency-tagging EEG and eye tracking reveal reduced social bias in boys with autism spectrum disorder

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