Effect of Copper Supplementation in Middle Aged People on Plasma Anti-Oxidants and Red Blood Cell Oxidizability

Rock, Edmond; Mazur, Andrzej; Rayssiguier, Yves; Kehoe, Claire A.; O’Connor, Jacqueline M.; Bonham, Maxine P.; Strain, Sean

doi:10.1007/0-306-47466-2_150

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the EUfunded FOODCUE Study -a collaboration between the Unité Maladies Métaboliques et Micronutriments (INRA-CRNH), France and the University of Ulster -found decreased susceptibility of red blood cells to peroxidation following supplementation of healthy men and women with copper. This decreased susceptibility occurred without changes in copper/zinc SOD activity and it was concluded that intake of copper as high as 7 mg day 21 has no pro-oxidant activity and may result in protection of red blood cells against oxidation 40 . Some studies have suggested that atherogenesis occurs as a result of copper overload.…”

Section: Extracellularmentioning

confidence: 95%

A review of the MAFF Optimal Nutrition Status research programme: folate, iron and copper

Buttriss

Hughes²

2002

Public Health Nutr.

View full text Add to dashboard Cite

Objective: The objective was to conduct a critical appraisal of research conducted within one of the UK government's research programmes, Optimal Nutrition Status, and to place the findings of this work in the context of the international research effort, to assist policy makers and advisers. Nine nutrients are addressed within the programme; the findings for three of these are reported here: folate/folic acid, iron and copper. Design: To conduct the review, the researchers had access to all unpublished progress reports, submitted to officials, arising from the projects. The overall assessment criterion was whether the information generated by the research programme could be regarded as reliable experimental data of direct relevance to setting optimal dietary requirements for the particular micronutrients. However, findings were also assessed against specific scientific criteria concerning understanding of the bioavailability, interactions, development of functional markers and inter-individual variations in metabolism, for each of the nutrients scrutinised.

show abstract

Section: Extracellularmentioning

confidence: 95%

A review of the MAFF Optimal Nutrition Status research programme: folate, iron and copper

Buttriss

Hughes²

2002

Public Health Nutr.

View full text Add to dashboard Cite

show abstract

“…A further study was carried out at the same research centre as part of an EU collaborative study to determine the susceptibility of red blood cells (RBC) to peroxidation following supplementation of healthy men and women with Cu, and this study found a decreased susceptibility that occurred without changes in SOD activity. The researchers concluded that intake of Cu as high as 7 mg/day has no pro‐oxidant activity and may result in protection of RBC against oxidation (Rock et al 2000).…”

Section: Functionmentioning

confidence: 99%

An update on copper: contribution of MAFF‐funded research

Buttriss

Hughes

2000

Nutrition Bulletin

View full text Add to dashboard Cite

This paper summarises the findings with respect to copper of the British Nutrition Foundation's recent review of the outcomes of the Ministry of Agriculture, Fisheries and Food's Optimal Nutrition Status research programme and identifies future research requirements. The typical human adult body contains approximately 100 mg of copper (Cu), the majority of which is tightly bound to about 30 enzymes and proteins. Cu is an essential transition element that plays a fundamental role in biochemistry by permitting the transfer of electrons in critical metabolic pathways. The paper provides an overview of current knowledge about the function, sources and habitual intakes of copper in the UK; absorption, bioavailability and metabolic regulation; and assessment or indicators of human copper status. Further research requirements to determine optimal nutrition status for copper were identified in the review and refined at a workshop of experts. These have been presented to the Food Standards Agency and are included in the paper.

show abstract

Effect of Copper Supplementation in Middle Aged People on Plasma Anti-Oxidants and Red Blood Cell Oxidizability

Cited by 2 publications

References 0 publications

A review of the MAFF Optimal Nutrition Status research programme: folate, iron and copper

A review of the MAFF Optimal Nutrition Status research programme: folate, iron and copper

An update on copper: contribution of MAFF‐funded research

Contact Info

Product

Resources

About