Effect of Corticosteroid Treatment and Enucleation on the Visual Prognosis of Sympathetic Ophthalmia

Missed perforation presenting as sympathetic ophthalmia in an adolescent Malay girl

“…It has a generally good prognosis rate with timely treatment and regular follow-up 5. The concern in this case is usage of steroids in a growing child.…”

“…Intensive systemic and topical corticosteroid therapy has improved the outcome and reduced the relapse rate of SO 1 5. It has a generally good prognosis rate with timely treatment and regular follow-up 5.…”

Repositioning of a Traumatically Displaced Globe With Maxillary Antrostomy: Review of the Literature and Treatment Recommendations

“…22 Published studies have reported the incidence of SO after penetrating globe injury to be 0% to 1.9% and to occur as early as 5 days to as late as 42 years after the injury. 23,24 Patients diagnosed with SO should initially be treated with corticosteroids, 18,19,21,[25][26][27][28][29] with or without the addition of immunosuppressive agents. 19,28 Large doses of steroids should be given immediately if SO is suspected and should be continued for several months after the resolution of symptoms.…”

“…19,28 Large doses of steroids should be given immediately if SO is suspected and should be continued for several months after the resolution of symptoms. 18,26 In cases in which corticosteroids alone are ineffective in the management of SO, immunosuppressive agents such as cyclosporine A, methotrexate, or azathioprine can be added. 18,30 The use of steroids for patients with ocular trauma is indicated, not only to prevent the possible development of SO, but also to treat traumatic optic neuropathy (TON).…”

Multimodality Diagnostic Imaging in a Case of Sympathetic Ophthalmia

“…While SO is considerably rare, the significant morbidity of the disease makes it an important differential in cases of bilateral panuveitis. 1 Immunosuppression, particularly with oral steroids, remains the staple for therapy. Treatment response is typically monitored by clinical findings, fluorescein angiography, ultrasonography, and optical coherence tomography.…”