Primigravida has impacts related to preparedness for the transition into motherhood. Thus, its can disrupt the attachment between the mother and the fetus. This study aimed to determine the effects of prenatal spiritual-based stimulation on maternal-fetal attachment. This study employed a quasi-experimental design with a control group and was conducted among primigravida women in Indonesia. The study included 66 respondents selected through purposive sampling. They were divided into the intervention and control groups, each comprising 33 participants. The intervention group received prenatal spiritual-based stimulations, which involved auditory, kinesthetic, light, and temperature stimulations and were administered over a 12-week period. Data on maternal-fetal attachment were collected using the Prenatal Attachment Inventory (PAI), which had been tested for validity and reliability. Approval to use the instrument was obtained from its original author. Data analysis was performed using the Wilcoxon and Mann Whitney tests. The results showed that the Wilcoxon test yielded a p-value of 0.000 or significant differences were observed before and after intervention for the intervention group and 0.059 no significant differences were observed before and after the intervention for the control group. The Mann Whitney test revealed a p-value of 0.000, there were differences in the maternal-fetal attachment before and after the intervention. Therefore, spiritual-based prenatal stimulation is effective in enhancing maternal-fetal attachment. These results can provide a basis for pregnant women to apply spiritual-based prenatal stimulation interventions to enhance maternal-fetal attachment and health status.