Effect of cream formulation of fenugreek seed extract on some mechanical parameters of human skin

Abstract

Purpose: To determine the effect of an emulsion formulation of fenugreek (Trigonella Foneum-Graecum L) seed extract on some mechanical parameters of the skin of healthy human volunteers Methods: A water-in-oil emulsion cream base without fenugreek seed extract which served as control, and a similar formulation containing 4 %w/v of the extract in the internal (aqueous) phase were prepared. Each of the formulations was applied to the cheeks of 10 human volunteers for a period of 4 weeks and some mechanical parameters (R0, R1, R2, R3, R4, R5, R6, R7, R8 and R9) of the skin were measured weekly using Cutometer MPA 580. Results: The results indicate that the effects of the creams on skin mechanical properties were significant (p < 0.05) with respect to time, except for R4 and R9. The extract-containing cream substantially increased skin elasticity, hydration and the ability of skin to resist photo-aging when compared to the base. Conclusion: Both the cream base and the cream containing fenugreek extract demonstrated significant (p < 0.05) improvement in all mechanical parameters related to skin elasticity, ageing, hydration and fatigue but the effect of the extract cream was more pronounced in some cases.

Screening of various botanical extracts for antioxidant activity using DPPH free radical method

“…These compounds are potent antioxidants (Akhtar et al, 2010). Extracts of soybeans and tamarind showed 83.45% and 79.2% free radical scavenging activity, respectively which were significantly (P<0.05) different from each other as well as significantly (P<0.05) different from that of Vitis vinifera.…”

Content of biogenic elements and fatty acid composition of fenugreek seeds cultivated under different conditions

“…Fenugreek seeds contain chemical compounds which are highly valued in the cosmetics industry. Akhtar et al (2010) reported that cream bases and cream formulations containing fenugreek seed extract substantially improved skin elasticity, hydration and skin's ability to resist photo-aging.…”

In vivo evaluation: the effects of a cream containing Acacia bark extract on skin melanin and erythema content

“…condensed tannin and phlobatannin, gallic acid, protocatechuic acid pyrocatechol, (+)-catechin, (-) epigallocatechin-7-gallate, and (-) epigallocatechin-5,7-digallate. The bark is also reported to contain (-) epicatechin, (+) dicatechin, quercetin, gallic acid, (+) leucocyanidin gallate, sucrose and (+) catechin-5-gallate [7]. However, the inhibitory effect of catechins on melanogenesis has been reported, gallic acid inhibits melanin synthesis of B16 melanoma.…”

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