2024
DOI: 10.1111/rda.14576
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Effect of cryopreservation on Odc1 and RhoA genes expression in diapausing mouse blastocysts

Sergei Amstislavsky,
Eugeny Brusentsev,
Daria Lebedeva
et al.

Abstract: The possibility of embryo cryopreservation is important for applying the genome resource banking (GRB) concept to those mammalian species that exhibit embryonal diapause in their early development. Odc1 encodes ODC1, which is a key enzyme in polyamine synthesis. RhoA is an essential part of Rho/ROCK system. Both Odc1 and RhoA play an important role in preimplantation embryo development. Studying these systems in mammalian species with obligate or experimentally designed embryonic diapause may provide insight i… Show more

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