Effect of Curcumin Supplementation on Exercise-Induced Oxidative Stress, Inflammation, Muscle Damage, and Muscle Soreness

Basham, Steven A.; Waldman, Hunter S.; Krings, Ben M.; Lamberth, John; Smith, JohnEric W.; McAllister, Matthew J.

doi:10.1080/19390211.2019.1604604

Cited by 62 publications

(63 citation statements)

References 31 publications

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“…The experimental process is carried out for 4 weeks or about 30 days. Previous studies conducted by Basham et al [17] produced results that were almost similar to this study. Experiments carried out for 28 days are still considered lacking to be able to see the effect of curcumin supplementation on the recovery process.…”

Section: Resultssupporting

confidence: 91%

“…In addition, curcumin is also widely used in sport and exercise physiology fields [11,12]. Some of the curcumin's potentials are as an anti-fatigue and recovery booster substance [13][14][15][16][17][18][19]. The term of fatigue that's explained before is a fatigue caused by workload or exercise and related to human physiological functions/physiological fatigue [20].…”

Section: Introductionmentioning

confidence: 99%

“…As the definition of fatigue described above, some studies related to curcumin as an anti-fatigue and recovery booster are divided into two groups. Several studies [13][14][15][16][17][18][19] examined the effect of curcumin related to central fatigue. The study concluded that curcumin can significantly reduce central fatigue indicators such as IL-6 and IL-1.…”

Section: Introductionmentioning

confidence: 99%

“…Some previous studies related to the effect of curcumin as anti-fatigue and recovery booster are still carried out in the acute study model [13][14][15][16]18]. There are very few studies that use curcumin in the form of the chronic study, especially in relation to anti-fatigue and recovery booster [17]. In the other hand, the effect of curcumin on recovery process following peripheral fatigue in human model study is need to be more investigated [19].…”

Section: Introductionmentioning

confidence: 99%

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Curcumin Supplementation and Its Effect on Recovery Process Following Peripheral Fatigue

Ali¹,

Ray²,

Rusdiana³

2019

Proceedings of the 5th International Conference on Physical Education, Sport, and Health (ACPES 2019)

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The purpose of this study was to determine the ability of curcumin for accelerating the recovery process after peripheral fatigue in human; as well as lactate clearance (LC), decrease of heart rate (DHR) and the recovery of vertical jump performance identified by the leg power (LP) and jump height (JH). 18 healthy men (age = 19.68 ± 0.7 y.o; BMI = 20.94 ± 1.43 Kg/m2; VO2Max = 49.30 ± 3.5 ml/kg/min) were divided into two groups (experiment and control) carried out the experimental trial for 4 weeks. Endurance training using ergocycle with moderate intensity (50-70% HRMax) was done 3 times a week. 1.1 gram/day curcumin consumed by experimental group and the control group was given a placebo sugar within. Measurements were made three times; baseline, week 2 and week 4. Experimental group showed increase of DHR. On the other way, LC only significantly increase at week 4 compared with the baseline. However, vertical jump performance recovery did not significantly increase. Comparing with the control group, only leg power recovery is significantly different, yet the mean of the experimental group mostly greater than control. The conclusion of this current results indicated that curcumin supplementation has potential to accelerate the recovery process due to peripheral fatigue.

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Section: Resultssupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Curcumin Supplementation and Its Effect on Recovery Process Following Peripheral Fatigue

Ali¹,

Ray²,

Rusdiana³

2019

Proceedings of the 5th International Conference on Physical Education, Sport, and Health (ACPES 2019)

View full text Add to dashboard Cite

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“…In addition, Delecroix et al [31] chose a combination of curcumin plus piperine in the composition. Regarding the daily dose of curcumin, seven studies used doses ranging from 150 to 1500 mg [1,2,4,5,10,24,25,30,32], and two studies tested higher doses of about 5 g [28] and 6 g [31] daily. In nine of the included studies, supplementation was given before and after exercise [1,2,5,10,25,28,[30][31][32], Sciberras et al [4] used curcumin before exercise, and Nakhostin-Roohi et al [24] supplemented with curcumin after exercise.…”

Section: Characteristics Of the Studiesmentioning

confidence: 99%

Modulation of Exercise-Induced Muscle Damage, Inflammation, and Oxidative Markers by Curcumin Supplementation in a Physically Active Population: A Systematic Review

et al. 2020

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Physical activity, particularly high-intensity eccentric muscle contractions, produces exercise-induced muscle damage (EIMD). The breakdown of muscle fibers and the consequent inflammatory responses derived from EIMD affect exercise performance. Curcumin, a natural polyphenol extracted from turmeric, has been shown to have mainly antioxidant and also anti-inflammatory properties. This effect of curcumin could improve EIMD and exercise performance. The main objective of this systematic review was to critically evaluate the effectiveness of curcumin supplementation on EIMD and inflammatory and oxidative markers in a physically active population. A structured search was carried out following Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines in the databases SCOPUS, Web of Science (WOS), and Medline (PubMed) from inception to October 2019. The search included original articles with randomized controlled crossover or parallel design in which the intake of curcumin administered before and/or after exercise was compared with an identical placebo situation. No filters were applied to the type of physical exercise performed, the sex or the age of the participants. Of the 301 articles identified in the search, 11 met the established criteria and were included in this systematic review. The methodological quality of the studies was assessed using the McMaster Critical Review Form. The use of curcumin reduces the subjective perception of the intensity of muscle pain; reduces muscle damage through the decrease of creatine kinase (CK); increases muscle performance; has an anti-inflammatory effect by modulating the pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-8; and may have a slight antioxidant effect. In summary, the administration of curcumin at a dose between 150–1500 mg/day before and during exercise, and up until 72 h’ post-exercise, improved performance by reducing EIMD and modulating the inflammation caused by physical activity. In addition, humans appear to be able to tolerate high doses of curcumin without significant side-effects.

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Curcumin and its nano‐formulations combined with exercise: From molecular mechanisms to clinic

Liu,

Wang,

Guo

et al. 2024

Cell Biochemistry & Function

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Curcumin is a strong substance derived from turmeric, a popular spice, renowned for its antioxidant and anti‐inflammatory abilities. The study delved deeply into a thorough examination of various sources to evaluate the impact of both regular curcumin and nano‐formulated curcumin on elements that impact physical performance, including muscular strain, discomfort, swelling, and oxidative tension. While engaging in exercise, the body experiences a rise in reactive oxygen species and inflammation. As a result, it is important to ensure a proper balance between internal and external sources of antioxidants to maintain stability in the skeletal muscle. Without this balance, there is a risk of muscle soreness, damage, and ultimately, a decline in exercise performance. Curcumin possesses the ability to enhance physical performance and reduce the symptoms of muscle fatigue and injury by virtue of its antioxidative and anti‐inflammatory properties. Including curcumin supplements appears to have advantageous effects on various aspects of exercise, such as enhancing performance, assisting with recovery, lessening muscle damage and discomfort, and lowering levels of inflammation and oxidative stress. However, a thorough assessment is necessary to precisely gauge the healing advantages of curcumin in enhancing exercise ability and reducing recovery time.

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Effect of Curcumin Supplementation on Exercise-Induced Oxidative Stress, Inflammation, Muscle Damage, and Muscle Soreness

Cited by 62 publications

References 31 publications

Curcumin Supplementation and Its Effect on Recovery Process Following Peripheral Fatigue

Curcumin Supplementation and Its Effect on Recovery Process Following Peripheral Fatigue

Modulation of Exercise-Induced Muscle Damage, Inflammation, and Oxidative Markers by Curcumin Supplementation in a Physically Active Population: A Systematic Review

Curcumin and its nano‐formulations combined with exercise: From molecular mechanisms to clinic

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