Effect of Date Fruits, Phoenix Dactyliferia L., on the Hemolytic Activity of Streptolysin O

A review of the chemistry and pharmacology of the date fruits (Phoenix dactylifera L.)

“…Further at low concentrations the date extract neutralized the hemolytic activity of the streptococcal exotoxin, streptolysin O, probably due to erythrocyte membrane stabilization and inhibition of streptolysin O enzyme. Fractionated studies showed that the inhibitory substance was steroidal in nature and not proteinaceous as deproteinization of the extract did not decrease its inhibitory effect (Abuharfeil et al, 1999). Independent investigations have shown that the anthocyanins, carotenoids, procyanidins and flavonoids present in dates are known to possess membrane protective effects (Hocman, 1988;Tapas et al, 2008) and it is quite possible that these compounds may have protected the erythrocyte membrane from damage.…”

Comparative study of neuropharmacological, analgesic properties and phenolic profile of Ajwah, Safawy and Sukkari cultivars of date palm (Phoenix dactylifera)

“…Date fruits are taken alone or in combination with other ingredients to get relief from asthma (Zaid and Arias-Jiménez 2002), to reduce wrinkling of the skin (Bauza et al 2001), as an expectorant and ameliorating in cough, bronchitis, respiratory disorders, to alleviate headache, to treat sexual debility and to increase immunity (Selvam 2008; Zaid and Arias-Jiménez 2002). Investigations revealed that date palm possesses antioxidant, antimutagenic (Vayalil 2002), antihaemolytic (Abuharfeil et al 1999), antiviral (Jassim and Naji 2010), antifungal (Shraideh et al 1998), anti-inflammatory (Mohamed and Al-Okabi 2004), antihyperlipidemic (Al-Maiman 2005), hepatoprotective (Al-Qarawi et al 2004; Sheikh et al 2014), nephroprotective (Al-Qarawi et al 2008), gastroprotective (Al-Qarawi et al 2005), anticancer (Ishurd and Kennedy 2005), immunostimulating (Puri et al 2000), and gonadotropic (El-Mougy et al 1991) activity. The date fruit is also rich in pharmacologically important phytochemical constituents including simple pheolics ( p -hydroxy benzoic acid, protocatechuic acid, gallic acid, vanillic acid, syringic acid), phenylpropanoids (cinnamic acid, caffeic acid, o -caffeoyl shikimic acid, ferulic acid, sinapic acid, o -coumaric acid, p -coumaric acid) (Mansouri et al 2005), carotenoids (β-carotene, lutein), sterols (cholesterol, campesterol, stigmasterol, β-sitosterol, isofucosterol) (Kikuchi and Miki 1978), flavonoids and their glycosides (catechin, epi -catechin, quercetin, luteolin, apigenin) (Hong et al 2006), procyaninidins (Hong et al 2006), and anthocyanins (Al-Farsi et al 2005).…”

Investigation of Enteric Gram-Negative Bacilli Contamination in Mazafati Date

“…None of the cases indicated contamination to Enterobacteriaceae, E.coli and enterococcus; however, coliform contamination was observed in a small number of samples. Seemingly this is an indication for anti-http://www.ispacs.com/journals/jgmi/2013/jgmi-00007/ International Scientific Publications and Consulting Services bacterial characteristic of dates (Abuharfeil et al 1999 [1]; Hammed and Sallal, 2002 [3]; Sabah et al 2007 [12]; Sadikin et al 2008 [13]; Sayyedi et al 2006 [14]; Shariati et al 2010 [15]). In this regard, several studies have been conducted to confirm the anti-bacterial properties of dates.…”

“…This is probably due to the inhibitory effects on this complication (Sayyedi et al 2006) [14]. There are also some reports on the positive effects of date extract in preventing the microorganism growth such as streptococcus (Abuharfeil et al 1999) [1]. Also, there was another study indicating the anti-viral effect of date palm kernel extract against phagocytic Pseudomonas aeruginosa and proving that the extract can be a good deterrent against this phage (Sabah et al 2007) [12].…”