Effect of delayed umbilical cord clamping on blood gas analysis

Valero, J. L.; Desantes, Domingo; Perales‐Puchalt, Alfredo; Rubio, J M Rubio; Almela, Vicente Diago; Perales, Alfredo

doi:10.1016/j.ejogrb.2012.01.020

Cited by 50 publications

(43 citation statements)

References 9 publications

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“…Andersson et al found that the umbilical cord pH and pCO 2 were not significantly different between DCC and ICC groups [36]. However, Valero J et al reported a significant decrease in pH, oxygen saturation, glucose level, oxygen content, bicarbonate, and base excess, and an increase in lactate and pCO 2 in umbilical cord samples following DCC [37]. Nevertheless, the infants in this study were vigorous and there was no association between the clinical picture and laboratory results.…”

Section: Term Infantscontrasting

confidence: 46%

Time to Delay: A Literature Review of Delayed Cord Clamping

2013

J Neonatal Biol

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Section: Term Infantscontrasting

confidence: 46%

Time to Delay: A Literature Review of Delayed Cord Clamping

2013

J Neonatal Biol

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“…The average number of adjustments during resuscitation was similar in both groups (median 27, IQR (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35) vs. 28 (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36); P = 0.796). (Figure 1b), however the oxygen need was highly variable in both the automated (IQR (0.52-0.98)) and the manual group (IQR (0.37-0.72)).…”

Section: Resuscitationmentioning

confidence: 96%

“…Early SpO 2 is related not only to FiO 2 , but also to factors like adequate functional residual capacity (34) and perinatal procedures like delayed cord clamping (35). In addition, rising need for oxygen can be a symptom of a pathological condition such as pneumothorax or of a ventilation-related complication, e.g., tube dislocation.…”

Section: Discussionmentioning

confidence: 99%

Fully automated predictive intelligent control of oxygenation (PRICO) in resuscitation and ventilation of preterm lambs

et al. 2015

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Articles Translational Investigation nature publishing groupBackground: Hyperoxia and hypoxia influence morbidity and mortality of preterm infants. Automated closed-loop control of the fraction of inspired oxygen (FiO 2 ) has been shown to facilitate oxygen supplementation in the neonatal intensive care unit (NICU), but has not yet been tested during preterm resuscitation. We hypothesized that fully automated FiO 2 control based on predefined oxygen saturation (SpO 2 ) targets was applicable in both preterm resuscitation and ventilation. Methods: Twenty-two preterm lambs were operatively delivered and intubated in a modified EXIT procedure. They were randomized to receive standardized resuscitation with either automated or manual FiO 2 control, targeting SpO 2 according to the Dawson curve in the first 10 min and SpO 2 90-95% hereafter. Automated FiO 2 control also was applied during surfactant replacement therapy and subsequent ventilation. results: Time within target range did not differ significantly between manual and automated FiO 2 control during resuscitation, however automated FiO 2 control significantly avoided hyperoxia. Automated FiO 2 control was feasible during surfactant replacement and kept SpO 2 within target range significantly better than manual control during subsequent ventilation. conclusion: In our model, fully automated FiO 2 control was feasible in rapidly changing physiologic conditions during postnatal resuscitation and prevented hyperoxia. We conclude that closed loop FiO 2 control is a promising tool for the delivery room.o xygen supplementation is one of the most common therapeutic interventions in resuscitation and neonatal intensive care of term and preterm infants (1). However, both hypoxia and hyperoxia must be avoided because of their detrimental effects on morbidity and mortality in these children. While hypoxia may lead to direct and indirect cellular damage, hyperoxia has been associated with oxygen toxicity, oxidative stress (2), and chronic diseases of preterm infants such as bronchopulmonary dysplasia (3) and retinopathy of prematurity (4).Increase in oxygenation after birth is a gradual process (5). Measurement of oxygen saturation (SpO 2 ) by pulse oximetry in the delivery room is feasible in newborn resuscitation (6) and in preterm infants within the first minutes of life (7). SpO 2 reference values of preterm infants increase within the first 10 min of life (5). This has led to SpO 2 target values incorporated in the current European Resuscitation Council guidelines on resuscitation of newborns (8). In order to avoid hyperoxia, current recommendations advise resuscitation of preterm infants with a mixture of air and oxygen, and to use fraction of inspired oxygen (FiO 2 ) between 0.21 and 0.30 (9). FiO 2 should subsequently be titrated according to SpO 2 (10,11). General use of pulse oximetry has been shown to extensively reduce O 2 -derived toxicity in preterm infants (12). However, keeping SpO 2 manually within changing saturation limits during a hectic period of resu...

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“…3 Cord compression during the second stage of labour may increase hypovolaemia after ECC, resulting in a baby that responds poorly to resuscitation because of the failure of adequate placental transfusion, with the result that the baby urgently requires an emergency transfusion of un-crossmatched O-negative blood. 4 The paediatrician, faced with a severely hypovolaemic baby, is in no position to raise the issue of the timing of cord clamping at that stage.…”

Section: Referencesmentioning

confidence: 99%

“…In this situation, uterine repair is a simpler procedure to perform than hysterectomy, and as we revealed, carried a relatively low mortality rate of <5%. Ethiopian-based studies from Kelly and colleagues, 3,4 together with a Saudi Arabian study 5 have usefully followed up women after uterine repair and demonstrate that delivery by elective caesarean section is safe. As Kelly rightly points out, it is essential that women who have had a uterine rupture stay in maternity waiting areas/houses for 2 or 3 weeks before their expected delivery date, ensuring rapid access to hospital facilities when labour begins.…”

mentioning

confidence: 99%

The missing peripartum deleterious process may be early cord clamping

Hutchon

2013

BJOG

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Effect of delayed umbilical cord clamping on blood gas analysis

Cited by 50 publications

References 9 publications

Time to Delay: A Literature Review of Delayed Cord Clamping

Time to Delay: A Literature Review of Delayed Cord Clamping

Fully automated predictive intelligent control of oxygenation (PRICO) in resuscitation and ventilation of preterm lambs

The missing peripartum deleterious process may be early cord clamping

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