Effect of detomidine or romifidine constant rate infusion on plasma lactate concentration and inhalant requirements during isoflurane anaesthesia in horses

Barrio, MC Niimura del; Bennett, Rachel C.; Hughes, J. M. L.

doi:10.1016/j.vaa.2016.01.002

Cited by 10 publications

(7 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Firstly, at this practice, most horses received an alpha 2 agonist CRIs during anaesthesia: this has not been reported in earlier anaesthetic mortality studies. These drugs are known to have a significant anaesthetic-sparing effect [ 26 – 28 ], which may contribute to a reduction in the risk of complications during recovery. In addition, all horses received sedation in recovery, and the use of sedation early in recovery is associated with significantly better recovery scores [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

A retrospective report (2003–2013) of the complications associated with the use of a one-man (head and tail) rope recovery system in horses following general anaesthesia

et al. 2018

View full text Add to dashboard Cite

BackgroundThe mortality rate of horses undergoing general anaesthesia is high when compared to humans or small animal patients. One of the most critical periods during equine anaesthesia is recovery, as the horse attempts to regain a standing position. This study was performed in a private equine practice in Belgium that uses a purpose-designed one-man (head and tail) rope recovery system to assist the horse during the standing process.The main purpose of the retrospective study was to report and analyse complications and the mortality rate in horses during recovery from anaesthesia using the described recovery system. Information retrieved from the medical records included patient signalment, anaesthetic protocol, duration of anaesthesia, ASA grade, type of surgery, recovery time and complications during recovery. Sedation was administered to all horses prior to recovery with the rope system. Complications were divided into major complications in which the horse was euthanized and minor complications where the horse survived. Major complications were further subdivided into those where the rope system did not contribute to the recovery complication (Group 1) and those where it was not possible to determine if the rope system was of any benefit (Group 2).ResultsFive thousand eight hundred fifty two horses recovered from general anaesthesia with rope assistance. Complications were identified in 30 (0.51%). Major complications occurred in 12 horses (0.20%) of which three (0.05%) were assigned to Group 1 and nine (0.15%) to Group 2. Three horses in Group 2 suffered musculoskeletal injuries (0.05%). Eighteen horses (0.31%) suffered minor complications, of which five (0.08%) were categorised as failures of the recovery system.ConclusionsThis study reports the major and minor complication and mortality rate during recovery from anaesthesia using a specific type of rope recovery system. Mortality associated with the rope recovery system was low. During recovery from anaesthesia this rope system may reduce the risk of lethal complications, particularly major orthopaedic injuries.

show abstract

Section: Discussionmentioning

confidence: 99%

A retrospective report (2003–2013) of the complications associated with the use of a one-man (head and tail) rope recovery system in horses following general anaesthesia

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The lack of licenced drugs in food producing animals makes maximisation of MAC sparing (decrease in the requirement of inhalant agent) through the use of regional anaesthesia an important part of food producing animal anaesthesia. Alpha-2 adrenergic agonist infusions are commonly used to decrease isoflurane requirements in horses [49]. In the cases discussed here, α-2 adrenergic agonists were not used due to a concern that further decreases in HR would be observed.…”

Section: Discussionmentioning

confidence: 99%

Use of adrenaline continuous infusion to treat hypotension during general anaesthesia in a cow and a calf

2020

View full text Add to dashboard Cite

Background: Hypotension is one of the most common complications observed during inhalation anaesthesia in veterinary patients. Treatment of hypotension in cattle is more challenging than in other species, owing to the limited number of drugs licensed in food producing animals. The use of adrenaline as an infusion to support blood pressure has not been described previously in bovines. Case presentation: A cow and a calf presented to University College Dublin Veterinary Hospital for bilateral mandibular fracture repair and bladder rupture repair respectively, developed severe anaesthetic related hypotension unresponsive to conventional treatments. In both cases an adrenaline infusion was started and slowly increased to effect, with infusion rates ranging from 0.01 to 0.25 μg/kg/min. Blood pressure increased as the adrenaline infusion rate increased, but clinically significant improvements in blood pressure were only observed with infusion rates exceeding 0.05 μg/kg/min. The side effect observed with adrenaline infusion was an increase in plasma lactate levels in both cases. Both animals were euthanised due to non-anaesthetic related complications. Conclusions: Maintenance of normotension is important during bovine anaesthesia to prevent the development of postanaesthetic complications. In the cases described here, adrenaline was effective as an additional treatment of anaesthetic related hypotension. Further research is required to establish the recommended infusion rates, cardiovascular effects and possible side effects of adrenaline infusion administration as a treatment for hypotension in bovines.

show abstract

“…Romifidine and detomidine are licensed alternatives and also have an isoflurane‐sparing effect (Niimura Del Barrio et al . ).…”

Section: Systemic Analgesicsmentioning

confidence: 97%

“…Dexmedetomidine or medetomidine do not have a marketing authorisation for administration to horses making their routine use difficult to justify. Romifidine and detomidine are licensed alternatives and also have an isoflurane-sparing effect (Niimura Del Barrio et al 2017).…”

Section: Alpha-2 Adrenoreceptor Agonistsmentioning

confidence: 99%

Perioperative pain management in horses

McFadzean

Love

2018

Equine Veterinary Education

View full text Add to dashboard Cite

Summary The inability to talk does not diminish an animal's ability to experience pain, although it may hinder its recognition and therefore lead to the under‐treatment of pain. Pain assessment and treatment in horses has advanced considerably with the recent publication of numerous research papers in this area. This review will summarise these research findings and suggest how advances in knowledge of perioperative pain management can be implemented in equine clinical practice.

show abstract

Effect of detomidine or romifidine constant rate infusion on plasma lactate concentration and inhalant requirements during isoflurane anaesthesia in horses

Cited by 10 publications

References 25 publications

A retrospective report (2003–2013) of the complications associated with the use of a one-man (head and tail) rope recovery system in horses following general anaesthesia

A retrospective report (2003–2013) of the complications associated with the use of a one-man (head and tail) rope recovery system in horses following general anaesthesia

Use of adrenaline continuous infusion to treat hypotension during general anaesthesia in a cow and a calf

Perioperative pain management in horses

Contact Info

Product

Resources

About