An experiment was conducted to study the effect of moringa leaf meal (MLM) at varying levels in the diet of quails on serum biochemical profile. One hundred and fifty day old quail chicks were randomly allotted into 5 experiment groups (T1, T2, T3, T4 and T5) each with 3 replicates of 10 chicks. MLM was incorporated at 0, 1.5, 3.0, 4.5 and 6.0% levels, respectively, in the different experimental groups. All the diets formulated were iso-caloric and iso-nitrogenous. At the end of the experiment, blood was collected from 2 birds/ replicate, thus a total of 30 birds and serum was separated. Results revealed that the albumin, calcium and phosphorus contents were increased (p<0.05), while glucose decreased (p<0.01) with increase in the level of MLM for 0 to 6.0 % in the diet. And the values for total protein and globulin increased (p>0.05), while triglycerides, total cholesterol and creatinine decreased (p>0.05) with linear increase of MLM in quail diets. Further, increase (p<0.05) in HDL Cholesterol level and decrease (p>0.05) in LDL and VLDL Cholesterol levels were recorded in serum with increased level of inclusion of MLM from 0 to 6.0 % in the diet. The present study indicated that moringa leaf meal can be included up to 6.0 % level in the diet of quails for production of low cholesterol meat without any adverse effects on production performance.