Effect of Dietary Oils on the Life Span of Senescence-Accelerated Mouse

Abstract

Experimental animal life span with dietary oil administration has been found to differ for stroke-prone spontaneously hypersensitive (SHRSP) rats and senescence-accelerated mouse (SAM-P8), but this parameter for the latter given rapeseed oil and perilla oil has yet to be examined in detail and hence the present study was carried out. Male SAM-P8 mice were provided a test diet prepared from soybean oil, rapeseed oil, perilla oil or olive oil, which served as 10% weight of fat intake. Body weight and food intake were found essentially the same in all animal groups, as was also mean life span. The effects of dietary oils on life span would thus appear to differ according to animal strain.