Effect of Dietary Sources and Levels of Copper Supplementation on Growth Performance, Blood Parameters and Slaughter Traits of Broiler Chickens

Abstract

This research paper was carried to determine the effect of dietary supplementation of copper at levels 50 and100 ppm, from various sources, inorganic (copper sulfate, CuSO4) or organic (copper-methionine, Cu-Met and copper-glycine, Cu-gly) on the productive traits, blood parameters, carcass traits and cecal bacterial count of broiler chickens. Three hundred and fifty Cobb 500 broiler chickens at 7 days of age were randomly divided into 7 groups (each of 50 birds): the 1 st group was fed a commercial basal diet without any supplementation (control), the 2 nd and 3 rd groups were fed control diet supplemented with 50 and 100 ppm of CuSO4, the 4 th and 5 th groups were fed control diet supplemented with Cu-Met at 50 and 100 ppm and the 6 th and 7 th groups were fed basal diet supplemented with Cu-gly at 50 and 100 ppm. Results showed that birds fed basal diet supplemented with inorganic or organic Cu had significantly better live body weight, weight gain, feed conversion ratio, economic efficiency and production index, while feed consumption was reduced compared with control group. However, the groups supplemented with organic Cu showed significantly improved on performance traits compared with the other groups. Supplementation of dietary Cu from different sources significantly decreased serum total lipids, triglycerides, cholesterol, low density lipoprotein, Aspartate aminotransferase, Alanine aminotransferase, creatinine and malondialdehyde. On the other hand supplementation of dietary Cu from different sources significantly increased the levels of red blood cells, hemoglobin, packed cell volume, glucose, globulin, alkaline phosphatase, triiodothyronine hormone, serum immunoglobulin (IgG and IgM) and total antioxidant capacity compared with the control group. Additionally, percentage of dressing and spleen were increased, while abdominal fat was decreased but not significant in Cu-supplemented birds. Moreover, Cu supplementation decreased total bacterial count (Salmonella, E. coli and Proteus) compared with the control. In conclusion, Cu supplementation with 100 ppm of Cu-gly or Cu-Met of diet were improved the growth performance, and physiological and immune response of broiler chickens. Broilers fed organic Cu had better growth and immune response than those fed inorganic Cu.

Mitigating the Growth, Biochemical Changes, Genotoxic and Pathological Effects of Copper Toxicity in Broiler Chickens by Supplementing Vitamins C and E

“…The reduction in HDL-C is due to hypocholesterolemia and hypoproteinemia in this inquiry, as more than 40% of HDL-C value represents cholesterol value and the remaining proteins [ 86 ]. The same findings were obtained by El-Hady and Mohamed [ 87 ] in broiler chickens with dietary supplementation of CuSO 4 at levels 50 and 100 ppm for 5 weeks. However, earlier studies exposed different outcomes, for example, rise of total lipid, cholesterol, and LDL-C with no variation HDL-C level in Cu-exposed quail [ 69 ] or no alteration in plasma total cholesterol levels in broilers [ 17 ].…”

The effect of feed supplementation with a copper-glycine chelate and copper sulphate on cellular and humoral immune parameters in chickens

“…One of the common strategies for correcting copper deficiencies in humans and animals is rationalization of the diet and the use of copper formulations as diet supplements (Nguyen et al, 2020). In poultry, dietary modifications mainly involve the use of compound feed supplemented with organic copper compounds, usually in the form of a glycine chelate (El-Ghalid et al, 2019).…”

Impact of Pumpkin Oil and Copper and Their Synergistic Effects on Productive Performance and Physiological Responses of Weaning Male Rabbits

“…When administered, this element has been revealed to be important for growth progress with antibacterial action (Charmaine and Hans, 2021). Copper appears as a cofactor of many antioxidant enzymes that are influence animal immunity of (El-Hady and Mohamed, 2019).…”