Effect of Dietary Starch-to-Fat Ratio on Lipid Metabolism, Inflammation, and Microbiota of Multiparous Sow and Newborn Piglets

Wang, Wenhui; Yu, Zhu; Yin, Xindi; Wang, Zijie; Xu, Song; Shi, Chuanxin; Zang, Jianjun; Liu, Hu; Wang, Fenglai

doi:10.3390/agriculture13051069

Cited by 2 publications

(1 citation statement)

References 55 publications

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“…The impact of improving the energy matrix did not interfere with the animal's immune status, which can be substantial; for example, sows fed a diet with a low ratio of starch and fat signi cantly increased the contents of IL-1β, IL-6, and TNF-α in plasma samples during parturition 13 . It is reasonable to infer that when formulating the diet, components related to the construction of the immune system should be considered, particularly focusing on dietary strategies that could potentially lead to excessive immune activation and hinder animal production e ciency 14 .…”

Section: Serum Cytokine Concentrationsmentioning

confidence: 99%

β-mannanase-supplemented diets reduced by 85 kcal of metabolizable energy/kg containing xylanase promotes benefits in fecal alpha diversity in lactating sows

Lima,

Engelsing,

Genova

et al. 2024

Preprint

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Enzyme-supplemented diets can influence the intestinal microbiome in an intricate interplay with the immune system. The effects of β-mannanase supplementation in metabolizable energy (ME)-reduced diets containing xylanase were investigated on cytokine profile and fecal microbiota in lactating sows (n = 60, 248.4 ± 2.4 kg) assigned in a randomized block design to 1 of 3 dietary treatments: a control diet containing xylanase (valorization of 40 kcal of ME/kg diet, CD40), CD40 + β-mannanase (0.3 g/kg, valorization of 45 kcal ME/kg diet, CD85), and CD40 + β-mannanase (0.3 g/kg, valorization of 60 kcal ME/kg diet, CD100). Serum cytokines concentrations were determined on day 18 of lactation. On day 21, fecal microbiota composition was characterized by 16S rRNA gene sequencing. Sows on CD85 had higher alpha diversity richness than CD100 based on the Simpson index. Acutalibacteraceae family was more abundant in sows fed CD100 than CD85 but CAG-508 and NSJ_53 families exhibited higher abundance in sows fed CD85 than CD100. Fimenecus genus exhibited lower abundance in sows on CD85 compared to CD40 or CD100. In conclusion, a diet supplemented with β-mannanase reduced by 85 kcal/kg containing xylanase during lactation can inhibit harmful bacteria, leading to changes in fecal alpha diversity in sows.

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Section: Serum Cytokine Concentrationsmentioning

confidence: 99%

β-mannanase-supplemented diets reduced by 85 kcal of metabolizable energy/kg containing xylanase promotes benefits in fecal alpha diversity in lactating sows

Lima,

Engelsing,

Genova

et al. 2024

Preprint

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Lipid Metabolism Indicators in Sow Blood Under the Influence of Iron and Germanium Nanocompounds

Karpovsky,

Krawchuk,

Danchuk

et al. 2024

Naukovì dopovìdì Nacìonalʹnogo unìversitetu bìoresursìv ì priro

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The relevance of the conducted research is determined by the lack of information in the available literature regarding the influence of iron and germanium nanoparticles on lipid exchange indicators in the plasma of sows. The aim of the study was to determine the effect of administering iron and germanium nanoparticles on lipid exchange indicators in the blood of sows before and after farrowing. The experiment was conducted on 24 large white sows, aged 2-3 years, which were divided into two groups (control and experimental). For ten days before farrowing, the sows in the experimental group were administered a complex of micronutrient compounds of iron – 3 mg/day and germanium – 0.01 mg/day. Blood plasma of the animals was used as material for the study, in which specific lipid exchange indicators were determined. The effect of farrowing on the content of triacylglycerols, non-esterified fatty acids, and total cholesterol in the blood plasma of animals was established (F= 33.0–156.0 > FU=2.9; P < 0.001). Before farrowing, there is a restructuring of lipid metabolism in sows, characterized by a decrease in the content of triacylglycerols and total cholesterol, and an increase in the content of non-esterified fatty acids in the blood plasma. It was found that within a day before farrowing, the content of triacylglycerols decreases by 30.6% (P≤0.001), total cholesterol by 18.3% (P≤0.01), and non-esterified fatty acids increase by 1.5 times (P≤0.001). Administering iron and germanium nanoparticles significantly affects the content of triacylglycerols (η²ᵪ=0.53; P≤0.05), total cholesterol (η²ᵪ=0.69; P≤0.01), and non-esterified fatty acids (η²ᵪ=0.50; P≤0.05) in the blood plasma of sows only on the day of farrowing. During this time, in the blood of sows administered metal nanoparticles, the content of triacylglycerols and total cholesterol is higher by 23.7% (P≤0.05) and 11.5% (P≤0.01), respectively, and the content of non-esterified fatty acids is lower by 9.2% (P≤0.05) compared to the indicators of animals in the control group. The prospects for further research lie in the development of modern methods to increase the productivity and resistance of sows using metal nanoparticles.

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Effect of Dietary Starch-to-Fat Ratio on Lipid Metabolism, Inflammation, and Microbiota of Multiparous Sow and Newborn Piglets

Cited by 2 publications

References 55 publications

β-mannanase-supplemented diets reduced by 85 kcal of metabolizable energy/kg containing xylanase promotes benefits in fecal alpha diversity in lactating sows

β-mannanase-supplemented diets reduced by 85 kcal of metabolizable energy/kg containing xylanase promotes benefits in fecal alpha diversity in lactating sows

Lipid Metabolism Indicators in Sow Blood Under the Influence of Iron and Germanium Nanocompounds

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