Boneless Tuna chunks were marinated using spices and were dried in a microwave vacuum dryer at different powers (600 W [T1], 650 W [T2], and 700 W [T3]) for 2 hr. Another two batches were prepared by hot air drying (55 ± 5°C) (HAD) and sun drying (SD) to a comparable moisture content obtained by sample T2. The moisture content was 44.69 g/100 g, 39.26 g/100 g, 24.40 g/100 g, 32.80 g/100 g, and 38.45 g/100 g for T1, T2, T3, SD, and HAD, respectively. Increasing microwave power level resulted in reduced moisture content and water activity in dried tuna chunks.