Potato is considered strategic vegetable crop in the entire world. So, two field experiments were conducted in the experimental farm, Faculty of Agriculture, Mansoura University to study the effect of organic fertilization and foliar application with potassium (K) as well as rates of K soil fertilization and their interaction on vegetative growth (plant height, No of leaves/plant, fresh and dry weight), leaves chemical composition (Chlorophyll a, b, a+b, N, P and K), tuber yield (plant yield, No. of tuber/plant and total tuber yield) and its quality (TSS, reducing, non reducing, total sugar, vitamin C, starch and protein). The experiment was conducted in strip split plot design including 12 treatments i.e. 2 organic applications (compost and vermicompost), 2 foliar applications (tap water as a control and K at 2%) and three rates of K soil applications (120, 165 and 214 kg K 2 O/hectare). The obtained results clarified that using compost and foliar application with K at 2% as well 165 kg K 2 O/ha significantly increased leaves chemical contents and tuber quality, while using vermicompost and foliar application with K at 2% plus 165 kg K 2 O/ha gave the highest values of potato growth parameters and yield. Thus, it can be recommended that using compost or vermicompost at 9.5 and 7 ton/ ha and foliar application with K at 2% as well 165 kg K 2 O/ha that gave the highest net return and improve quality of potato tubers.