Effect of Different Phosphorus Precursors on Biomimetic Hydroxyapatite Powder Properties

Abstract

Hydroxyapatite is the main component of natural hard tissues, such as teeth and bone. It has been studied extensively as a candidate biomaterial for its use in prosthetic applications. Hydroxyapatite was formulated as Ca10(PO4)6(OH)2 and it has a high stability under physiological conditions. Also hydroxyapatite can be synthesized using dierent calcium and phosphorus precursors. In this study, biomimetic hydroxyapatite powder has been synthesized simulating physiological conditions. Synthetic body uids which have the same composition as human blood plasma instead of pure water were used as precipitation media to obtain biological conditions. Recent research involved the eect of dierent Ca-precursors however aim of this study is to determine the eect of phosphorus resources. In this study, the synthesis of hydroxyapatite powder is carried out by using biomimetic method in synthetic body uids. OPA] were used as Ca-and P-precursors. Chemical structures of synthesized powders have been examined by Fourier transform infrared and X-ray diraction. Results showed that synthesized powders have a pure hydroxyapatite structure. However, ADHP precursors have an unfavorable eect on sintered hydroxyapatite powders. Using ADHP phase transition was caused in pure hydroxyapatite structure and apatite and whitlockite were observed as secondary phases. Their particle size, surface area determination and morphological structures have been characterized by Zeta-Sizer, biomimetic hydroxyapatite the BrunauerEmmettTeller analysis and scanning electron microscopy images, respectively. As a result dierent starting materials have aected the structure, particle size and morphological properties of biomimetic hydroxyapatite.

Facile synthesis of hydroxyapatite nanoparticles from eggshell biowaste usingAzadirachta indicaextract as a green template

“…[1][2][3][4][5] In recent years, hydroxyapatite nanoparticles (HANPs) have gained a lot of interest because of their use in various biomedical and industrial applications due to their outstanding bioactivity, biocompatibility, and osteoconductive properties. [6][7][8] Moreover, HANPs are also used for the removal of heavy metals from wastewater, 9,10 soil remediation, 11 catalysis, 12 column chromatography, 13,14 and food packaging applications. 15,16 The applications of HANPs are significantly influenced by particle size, shape, phase purity, crystallinity, morphology, and composition of nano-hydroxyapatite, which also depend on the synthesis precursors, synthesis routes, and processing parameters.…”

Heat treatment’s effects on hydroxyapatite powders in water vapor and air atmosphere

“…HA has a high stability under physiological conditions [2][3]. Synthetic hydroxyapatite which composes inorganic phase of bones and teeth is one of the biomedical materials for artificial bone, reconstruction of broken or disordered bones, coating of metallic biomedical materials and dental surgery with its great biocompatibility [4].…”

“…to synthesize HA. Because it is easy and economic, precipitation method is the most common technique [1][2][3]. However, the hydroxyapatite powder is produced with different methods a high amount of in the amorphous phase contains.…”

“…However, the hydroxyapatite powder is produced with different methods a high amount of in the amorphous phase contains. Also XRD patterns of synthesized amorphous HA structure could be turned to crystalline phase when it sintered at higher temperature without any or negligible transition [3].…”

“…[4] The structure of hydroxyapatite powder is decomposed at high temperatures. Changing the phase structure are cracked of hydroxyapatite pellets [2][3][4].…”