Two field experiments were conducted during late summer seasons of 2015-2016 at the Agric. Res. Station, Veg. Res. Dept., Hort. Res. Inst., Agric. Res. Center, in El-Arish, North Sinai Governorate, Egypt. The aim of this work was to study the effect of three tomato hybrids (Lycopersicon esculentum Mill.); i.e. one local "Eyeon" hybrid as well as two foreign hybrid (Alisa and GS-12) and two sources of organic fertilization each at 120 and 150 Kg N fed -1 (Chicken manure "ChM" and Cow manure) under sandy soil condition and high saline water with drip irrigation system. The treatments were arranged randomly in a split-plot design arrangement in randomized complete block design, in three replications where the three tomato hybrids were randomly arranged in the main plots, the two sources of organic fertilization were randomly distributed in sub plots. The results showed that, all growth parameters, (roots, leaves, and stems, as well as clusters fresh weight and both total fresh and dry weight) gave the highest values under "Eyeon" hybrid plantation and application of high rate (150 Kg N fed -1 ) from ChM followed by "GS-12" with the same of fertilization treatment. Yield and its components for early and total yield results showed that planting of local "Eyeon" hybrid with application the high rate of 150 kg Nfed -1 from ChM recorded the best values for yield characters i.e., number of fruits and fruit weight for grades A and B (g plant -1 and ton fed -1 ) as well as early and total yield for grade (A+B ton fed -1 .) compared to other treatments, in both seasons.Regarding to the fruit quality, the obtained results showed that fertilization of local "Eyeon" hybrid by ChM at the rate of 150 Kg N fed -1 recorded the highest values for pH, V.C, T.S.S in tomato fruit juice as well as fruit firmness and dry matter content in tomato fruits. The Local "Eyeon" hybrid was more responses to the high rate (150 Kg N fed -1 from ChM). For that it can recommend by cultivation the local "Eyeon" hybrid in North Sinai which it was more superior for produce high fruit yield with best quality when fertilized with chicken manure at the rate of 150 Kg N fed -1 under the condition of saline water irrigation compared with using the foreign tomato hybrids either Alisa or GS-12 which it is import from abroad.